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Remission in first-episode psychosis: Predictor variables and symptom improvement patterns
(2006)
Background: Previous attempts to identify clinically useful predictors of treatment outcome in schizophrenia have been hampered by methodological inconsistencies, including a lack of standardized outcome measures. Recently ...
Deficits in facial affect recognition in unaffected siblings of Xhosa schizophrenia patients: Evidence for a neurocognitive endophenotype
(2008)
The present study in an African Xhosa sample examined whether familial vulnerability to schizophrenia is associated with deficits in facial affect recognition. Healthy comparison subjects, unaffected siblings of schizophrenia ...
The factor structure for positive and negative symptoms in South African Xhosa patients with schizophrenia
(2001)
Most studies investigating the symptom dimensions of schizophrenia utilising the Scale for the Assessment of Negative Symptoms (SANS) and the Scale for the Assessment of Positive Symptoms (SAPS) favour a three factor model. ...
Topiramate in the treatment of trichotillomania: An open-label pilot study
(2006)
There is a need for an effective medication for the treatment of trichotillomania (TTM), which is an impulse control disorder characterized by chronic hair-pulling. Topiramate has shown promising results in the treatment ...
Remission in patients with first-episode schizophrenia receiving assured antipsychotic medication: A study with risperidone long-acting injection
(2008)
Recently proposed criteria for remission by a 'Remission in Schizophrenia Working Group' have generated considerable interest. We assessed rates, predictors, and correlates of remission in a sample of patients with ...
Escitalopram in the treatment of multisomatoform disorder: A double-blind, placebo-controlled trial
(2008)
Despite the prevalence of multisomatoform disorder (MSD), there are few controlled trials of its pharmacotherapy. The aim of this study was to compare the efficacy and safety of escitalopram (10-20 mg/day) with that of ...
Positive and negative symptoms in affected sib pairs with schizophrenia: Implications for genetic studies in an African Xhosa sample
(2005)
Careful phenotyping and the identification of subtypes of schizophrenia can contribute significantly to the success of genetic studies in schizophrenia. The phenomenology of schizophrenia in affected sib pairs has been ...
The effects of eicosapentaenoic acid in tardive dyskinesia: A randomized, placebo-controlled trial
(2006)
Objective: Worldwide, conventional antipsychotic medication continues to be used extensively, and tardive dyskinesia (TD) remains a serious complication. The primary objective of the present study was to compare the efficacy ...
Emotional face processing deficit in schizophrenia: A replication study in a South African Xhosa population
(2006)
Schizophrenia is associated with a deficit in the recognition of negative emotions from facial expressions. The present study examined the universality of this finding by studying facial expression recognition in African ...
Hoarding in obsessive-compulsive disorder: Clinical and genetic correlates
(2005)
Objective: Hoarding may be an important symptom dimension in obsessive-compulsive disorder (OCD). Hoarding in OCD has been associated with poor insight, poorer response to selective serotonin reuptake inhibitors than other ...