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Blood pressure patterns in pregnant patients on oral ketanserin

Steyn D.W.; Odendaal H.J. (2001)

Background. Ketanserin, a selective serotonin-2 receptor antagonist, decreases systolic blood pressure (SBP) and diastolic blood pressure (DBP) in non-pregnant patients with hypertension, but not in normotensive subjects. ...

Diurnal blood pressure variation in the evaluation of early onset severe pre-eclampsia

Steyn D.W.; Odendaal H.J.; Hall D.R. (2008)

Objective: : To study the association between diurnal variation in blood pressure, the mean daily blood pressure and various complications of pregnancy in patients presenting with severe pre-eclampsia before 34 weeks' ...

The optimal dosage of ketanserin for patients with severe hypertension in pregnancy

Van Schie D.L.; De Jeu R.M.; Steyn D.Wilhelm; Odendaal H.J.; Van Geijn H.P. (2002)

Objective: To establish the optimal dosage of ketanserin in the treatment of severe hypertension in pregnancy. Study design: A double blind prospective randomised controlled trail, comparing 10mg ketanserin given as ...

Placental histology related to fetal brain sonography

Rosier-van Dunne F.M.F.; Van Wezel-Meijler G.; Kaschula R.O.C.; Wranz P.A.B.; Odendaal H.J.; De Vries J.I.P. (2011)

Background: Chronic hypoxia and inflammatory processes can induce placental disturbances that may indirectly lead to perinatal brain injury. Objective: To study histological features of the placenta in relation to echogenicity ...

Is the prophylactic administration of magnesium sulphate in women with pre-eclampsia indicated prior to labour?

Hall D.R.; Odendaal H.J.; Smith M. (2000)

Objective: To determine whether prophylactic magnesium sulphate is necessary to prevent eclampsia and associated complications among women with pre-eclampsia prior to labour. Design: Case series. Setting: Tertiary referral ...

Evaluation of the use of umbilical artery Doppler flow studies and outcome of pregnancies at a secondary hospital

Hugo E.J.C.; Odendaal H.J.; Grove D. (2007)

Objective. To investigate the use of a personal computer (PC)-based, continuous-wave Doppler machine by a trained midwife at a secondary hospital to assess umbilical artery flow velocity waveforms (FVW) in referred women. ...

Severe early onset pre-eclampsia: Prognostic value of ultrasound and Doppler assessment

Geerts L.; Odendaal H.J. (2007)

Objective: Assess the prognostic value of ultrasound and Doppler parameters in severe preterm pre-eclampsia. Study design: Prospective cohort study in Cape Town, South Africa, involving 113 women with severe pre-eclampsia ...

Maternal and fetal single nucleotide polymorphisms in the epoxide hydrolase and gluthatione S-transferase P1 genes are not associated with pre-eclampsia in the Coloured population of the Western Cape, South Africa

Gerhardt G.S.; Peters W.H.M.; Hillermann R.; Odendaal H.J.; Carelse-Tofa K.; Raijmakers M.T.M.; Steegers E.A.P. (2004)

Oxidative stress is thought to play an important role in the pathophysiology of pre-eclampsia. A defect in certain enzymes responsible for detoxification may cause prolonged exposure to reactive by-products and contribute ...

Prevalence of genital mycoplasmas, ureaplasmas and chlamydia in pregnancy

Govender S.; Theron G.B.; Odendaal H.J.; Chalkley L.J. (2009)

The study was designed to determine the prevalence of genital mycoplasmas, ureaplasmas and Chlamydia on women attending their first prenatal visit, in conjunction with pre-term labour or HIV status. For pre-term labour ...

A randomised, double-blind placebo-controlled trial of ascorbic acid supplementation for the prevention of preterm labour

Steyn P.S.; Odendaal H.J.; Schoeman J.; Stander C.; Fanie N.; Grove D. (2003)

In a previous study from this institution, patients at high risk for preterm labour were screened for the presence of bacterial vaginosis (BV). When BV was present, they were randomised to receive either treatment ...