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Can uroflowmetry patterns in women be reliably interpreted?
Our aim was to investigate the proposition that uroflowmetry patterns can be reliably interpreted and correspond with specific urodynamic diagnoses. Uroflowmetry traces from 129 women with diagnoses of either genuine stress ...
Physiological induction of the acrosome reaction in human sperm: Validation of a microassay using minimal volumes of solubilized, homologous zona pellucida
Purpose: To develop a method that could accommodate microvolumes of solubilized human zona pellucida (ZP) and sperm for assessing the induction of the acrosome reaction. Methods: A microassay using 1 μl of 2.5, 1.25, 0.6, ...
Twice weekly vs. daily chemotherapy for childhood tuberculosis
Background. Treating childhood tuberculosis places a large burden on health services, and ways of lessening this were sought. Methods. A randomized controlled trial was conducted to determine the effectiveness of fully ...
A comparison of the effects of quetiapine ('Seroquel') and haloperidol in schizophrenic patients with a history of and a demonstrated, partial response to conventional antipsychotic treatment
Quetiapine ('Seroquel') is a well-tolerated, novel, atypical antipsychotic with consistent efficacy in the treatment of schizophrenia. To date, no clinical studies have evaluated the effect of quetiapine in patients who ...
Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: A randomised controlled trial
Objective. To determine whether nifedipine or prazosin is the more appropriate second-line antihypertensive agent in pregnancy. Design. Randomised controlled trial. Setting. Tygerberg Hospital, a tertiary referral centre. ...