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Clonogenic growth patterns correlate with chemotherapy response in acute myeloid leukaemia

Jacobs P.; Wood L. (2005)

Cytosine arabinoside and anthracycline-containing regimens induce remission in upwards of 60% of previously untreated patients with adult acute myeloid leukaemia (AML). Despite this, in addition to primary drug resistance, ...

Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: Two parallel randomized, placebo-controlled, double-blind clinical trials

Boffard K.D.; Riou B.; Warren B.; Choong P.I.T.; Rizoli S.; Rossaint R.; Axelsen M.; Kluger Y.; Champion H.R.; Lucas C.; Thompson E.; Ross S.; Jurkovich G.J.; Lynn M.; Pitts L.; Croce M.A. (2005)

Background: Uncontrolled bleeding is a leading cause of death in trauma. Two randomized, placebo-controlled, double-blind trials (one in blunt trauma and one in penetrating trauma) were conducted simultaneously to evaluate ...

Kaposi's sarcoma in kidney transplant recipients: A 23-year experience

Moosa M.R. (2005)

Background: Kaposi's sarcoma (KS) is a relatively common malignancy after kidney transplantation, accounting for up to 80% of all malignancies in developing countries. Aim: To assess the frequency of KS in renal transplant ...

Neurological abnormalities in first-episode schizophrenia: Temporal stability and clinical and outcome correlates

Emsley R.; Turner H.J.; Oosthuizen P.P.; Carr J. (2005)

Objective: Neurological abnormalities in subjects with schizophrenia have been regarded as diagnostically non-specific and non-localising. This study assessed the temporal stability of neurological abnormalities in subjects ...