Now showing items 1-10 of 13
Cytokine production in patients with tuberculous pericarditis
SETTING: An academic hospital in the Western Cape, South Africa. OBJECTIVE: To evaluate cytokine production (interferon-gamma [IFN-γ], interleukin-1 [IL-1], interleukin-2 [IL-2], interleukin-6 [IL-6], interleukin-10 [IL-10], ...
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures a prospective, controlled, randomized study of four hundred and fifty patients
Background: The treatment of open fractures of the tibial shaft is often complicated by delayed union and non-union. The objective of this study was to evaluate the safety and efficacy of the use of recombinant human bone ...
Phase II trial of ZD0473 as second-line therapy in mesothelioma
A phase II, open-label, non-comparative, multicentre trial of the platinum analogue ZD0473 as second-line therapy for pleural mesothelioma has been completed. The objectives were to evaluate the activity and tolerability ...
Mutations of the light meromyosin domain of the β-myosin heavy chain rod in hypertrophic cardiomyopathy
Familial hypertrophic cardiomyopathy (HCM) is caused by mutations in 9 sarcomeric protein genes. The most commonly affected is β-myosin heavy chain (MYH7), where missense mutations cluster in the head and neck regions and ...
The use of adenosine deaminase and interferon-γ as diagnostic tools for tuberculous pericarditis
Background: Traditional diagnostic tests for pericardial tuberculosis (TB) are insensitive and often require long culture periods, and this has led to more emphasis being placed on biochemical tests such as the pericardial ...
Effects of folic acid and zinc sulfate on male factor subfertility: A double-blind, randomized, placebo-controlled trial
Objective: To study the effects of folic acid and zinc sulfate treatment on semen variables in fertile and subfertile men. Design: Double-blind, placebo-controlled interventional study. Setting: Two outpatient fertility ...
Prospective evaluation of the American Urological Association symptom index and peak urinary flow rate for the followup of men with known urethral stricture disease
Purpose: We prospectively evaluated the American Urological Association (AUA) symptom index and maximum urine flow for predicting urethral stricture recurrence in men with a previous diagnosis of urethral stricture disease. ...
Therapeutic bronchoscopy for treatment-resistant COPD
[No abstract available]
Moclobemide is effective and well tolerated in the long-term pharmacotherapy of social anxiety disorder with or without comorbid anxiety disorder
Social phobia (social anxiety disorder) is a highly prevalent and chronic disorder that is associated with significant comorbidity and disability. Despite recent advances in the pharmacotherapy of the disorder, there is a ...
Quetiapine augmentation of serotonin reuptake inhibitors in obsessive - Compulsive disorder
The augmentation of serotonin reuptake inhibitors (SRIs) with atypical antipsychotics for the management of treatment-resistant obsessive-compulsive disorder (OCD) is gaining increasing acceptance. Quetiapine is a novel ...