Now showing items 1-10 of 12
Cytokine production in patients with tuberculous pericarditis
SETTING: An academic hospital in the Western Cape, South Africa. OBJECTIVE: To evaluate cytokine production (interferon-gamma [IFN-γ], interleukin-1 [IL-1], interleukin-2 [IL-2], interleukin-6 [IL-6], interleukin-10 [IL-10], ...
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures a prospective, controlled, randomized study of four hundred and fifty patients
Background: The treatment of open fractures of the tibial shaft is often complicated by delayed union and non-union. The objective of this study was to evaluate the safety and efficacy of the use of recombinant human bone ...
Phase II trial of ZD0473 as second-line therapy in mesothelioma
A phase II, open-label, non-comparative, multicentre trial of the platinum analogue ZD0473 as second-line therapy for pleural mesothelioma has been completed. The objectives were to evaluate the activity and tolerability ...
The optimal dosage of ketanserin for patients with severe hypertension in pregnancy
Objective: To establish the optimal dosage of ketanserin in the treatment of severe hypertension in pregnancy. Study design: A double blind prospective randomised controlled trail, comparing 10mg ketanserin given as ...
Juxta-renal inferior vena cava leiomyosarcoma
[No abstract available]
HHV-8 subtypes in South Africa: Identification of a case suggesting a novel B variant
Human herpesvirus 8 (HHV-8) has been identified as the causative agent for all forms of Kaposi's sarcoma and is also associated with the development of body cavity- based B-cell lymphomas and multicentric Castleman's ...
Moclobemide is effective and well tolerated in the long-term pharmacotherapy of social anxiety disorder with or without comorbid anxiety disorder
Social phobia (social anxiety disorder) is a highly prevalent and chronic disorder that is associated with significant comorbidity and disability. Despite recent advances in the pharmacotherapy of the disorder, there is a ...
Quetiapine augmentation of serotonin reuptake inhibitors in obsessive - Compulsive disorder
The augmentation of serotonin reuptake inhibitors (SRIs) with atypical antipsychotics for the management of treatment-resistant obsessive-compulsive disorder (OCD) is gaining increasing acceptance. Quetiapine is a novel ...
Evolution of the IS6110-based restriction fragment length polymorphism pattern during the transmission of Mycobacterium tuberculosis
Interpretation of the molecular epidemiological data of Mycobacterium tuberculosis is dependent on the validity of the assumptions that have been made. It is assumed that the IS6110 banding pattern is sufficiently stable ...
Posttraumatic stress and depressive symptomatology in a sample of battered women from South Africa
This study investigated the incidence of depression, posttraumatic stress symptomatology, anger, and guilt in a sample of 40 battered women in a shelter. Analysis indicated that 63% of the 40 scored moderate to severe on ...