Now showing items 1-10 of 14
Maternal HIV infection and antibody responses against vaccine-preventable diseases in uninfected infants
Context: Altered immune responses might contribute to the high morbidity and mortality observed in human immunodeficiency virus (HIV)-exposed uninfected infants. Objective: To study the association of maternal HIV infection ...
Virologic failure and second-line antiretroviral therapy in children in South Africa-the IeDEA Southern Africa collaboration
Background: With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determinants of virologic ...
Placental histology related to fetal brain sonography
Background: Chronic hypoxia and inflammatory processes can induce placental disturbances that may indirectly lead to perinatal brain injury. Objective: To study histological features of the placenta in relation to echogenicity ...
Impact of tuberculosis on maternal and child health
[No abstract available]
Delay and causes of delay in the diagnosis of childhood cancer in Africa
Background: Although a few studies have investigated delays in diagnosis and treatment among children and adolescents with cancer, this has never been subject of study in South Africa. Early diagnosis is fundamental as it ...
Lopinavir exposure is insufficient in children given double doses of lopinavir/ritonavir during rifampicin-based treatment for tuberculosis
Background: Coadministration of rifampicin dramatically reduces the concentrations of protease inhibitors. A pharmacokinetic study in healthy adults showed that doubling the dose of coformulated lopinavir/ritonavir was ...
A new species of Ixodes (Acari: Ixodidae) from South African mammals
A new tick species belonging to the African subgenus Afrixodes Morel, 1966, namely, Ixodes (Afrixodes) fynbosensis n. sp., is described. The female of I. fynbosensis is easily differentiated from the other African Ixodes ...
Rapid thermal responses and thermal tolerance in adult codling moth Cydia pomonella (Lepidoptera: Tortricidae)
In order to preserve key activities or improve survival, insects facing variable and unfavourable thermal environments may employ physiological adjustments on a daily basis. Here, we investigate the survival of laboratory-reared ...