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Treatment of obsessive-compulsive disorder by U.S. psychiatrists

Blanco C.; Olfson M.; Stein D.J.; Simpson H.B.; Gameroff M.J.; Narrow W.H. (2006)

Objective: To examine the treatment of obsessive-compulsive disorder (OCD) by a nationally representative sample of psychiatrists. Method: The authors analyzed physician-reported data from the 1997 and 1999 American ...

Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A meta-analysis of randomized controlled treatment trials

Fineberg N.A.; Stein D.J.; Premkumar P.; Carey P.; Sivakumaran T.; Vythilingum B.; Seedat S.; Westenberg H.; Denys D. (2006)

Small studies have shown positive effects from adding a variety of antipsychotic agents in patients with obsessive-compulsive disorder who are unresponsive to treatment with serotonin reuptake inhibitors. The evidence, ...

Escitalopram in obsessive-compulsive disorder: Response of symptom dimensions to pharmacotherapy

Stein D.J.; Carey P.D.; Lochner C.; Seedat Soraya; Fineberg N.; Andersen E.W. (2008)

Introduction: There is a substantial body of evidence that obsessive-compulsive disorder (OCD) symptoms can be grouped into a series of discrete dimensions, and some evidence that not all OCD symptom dimensions respond ...

A comparison of the effects of citalopram and moclobemide on resting brain perfusion in social anxiety disorder.

Warwick, James M.; Carey P.; Van der Linden G.; Prinsloo C.; Niehaus D.; Seedat S.; Dupont P.; Stein D.J. (2006)

INTRODUCTION: The serotonin specific reuptake inhibitor (SSRI) citalopram and the reversible mono-amine oxidase-A inhibitor (RIMA) moclobemide have both been used successfully for the treatment of social anxiety disorder ...

Opsoclonus-myoclonus in an HIV-infected child on antiretroviral therapy-possible immune reconstitution inflammatory syndrome

van Toorn R.; Rabie H.; Warwick, James M. (2005)

The exact immunopathogenesis and neuroanatomical localization of opsoclonus-myoclonus ataxia syndrome remains unclear. We describe a 1 year 9 month old girl who, shortly after commencement of highly active antiretroviral ...

Alcohol-induced psychotic disorder: brain perfusion and psychopathology--before and after anti-psychotic treatment.

Jordaan G.P.; Warwick, James M.; Nel D.G.; Hewlett R.; Emsley R. (2012)

Alcohol-induced psychotic disorder (AIPD) also known as alcohol hallucinosis is a rare complication of alcohol abuse. The pathogenesis and treatment of AIPD are still unclear. Few prospective treatment studies are available ...

High heritability of antimycobacterial immunity in an area of hyperendemicity for tuberculosis disease

Cobat, A.; Gallant, C. J.; Simkin, L.; Black, G. F.; Stanley, K.; Hughes, J.; Mark, Doherty T.; Hanekom, W. A.; Eley, B.; Beyers, Nulda; Jais, J.-P.; Van Helden, Paul D.; Abel, L.; Hoal, E. G.; Alcais, A.; Schurr, E. (2010)

Human antimycobacterial immunity is a critical component of tuberculosis (TB) pathogenesis that is often used to infer the presence of TB infection. We report high heritability (>50%) for in vitro secretion of tumor ...

Single Photon Emission Computed Tomography (SPECT) in obsessive-compulsive disorder before and after treatment with inositol

Carey P.D.; Warwick, James M.; Harvey B.H.; Stein D.J.; Seedat S. (2004)

Inositol, a glucose isomer and second messenger precursor, regulates numerous cellular functions and has demonstrated efficacy in obsessive-compulsive disorder (OCD) through mechanisms that remain unclear. The effect of ...

Should SPECT-CT replace SPECT for the evaluation of equivocal bone scan lesions in patients with underlying malignancies?

Ndlovu X.; George R.; Ellmann A.; Warwick, James M. (2010)

INTRODUCTION: Bone scintigraphy is used extensively in evaluating metastatic disease. There are currently no clear recommendations for the use of single photon emission computed tomography (SPECT)/CT in metastatic bone ...

Changes in regional brain volumes in social anxiety disorder following 12 weeks of treatment with escitalopram

Cassimjee N.; Fouche J.-P.; Burnett M.; Lochner C.; Warwick, James M.; Dupont P.; Stein D.J.; Cloete K.J.; Carey P.D. (2010)

It has been suggested that antidepressants, including the selective serotonin reuptake inhibitors have neurotrophic effects. Nevertheless, the impact of treatment with a selective serotonin re-uptake inhibitor on regional ...

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