Now showing items 31-40 of 62
TUNEL assay and SCSA determine different aspects of sperm DNA damage
Summary For the determination of sperm DNA damage, different assays are used. However, no further distinction is made and the literature generally speaks about DNA damage. Thus, this study aimed at comparing the sperm ...
Leucocytes and intrinsic ROS production may be factors compromising sperm chromatin condensation status
Considering that the final protection of the DNA against major assaults in terms of chromatin condensation is finalised in the epididymis, it is not known how sperm production of reactive oxygen species (ROS) and inflammatory ...
Rise in rifampicin-monoresistant tuberculosis in Western Cape, South Africa
SETTING: Brewelskloof Hospital, Western Cape, South Africa. OBJECTIVES: To verify the perceived increase in rifampicin monoresistant tuberculosis (RMR-TB) in the Cape Winelands-Overberg region and to identify potential ...
Tuberculosis contact investigation in a high-burden setting: House or household?
SETTING: A high tuberculosis (TB) burden setting, South Africa. Two frequently used definitions for 'household' are 1) 'all dwellings on the same plot of land that share the same residential address'; and 2) 'a group of ...
Early bactericidal activity of delamanid (OPC-67683) in smear-positive pulmonary tuberculosis patients
BACKGROUND: Delamanid (OPC-67683) is a novel mycolic acid biosynthesis inhibitor active against Mycobacterium tuberculosis at a low minimum inhibitory concentration. METHODS: Forty-eight patients with smear-positive ...
Early antiretroviral treatment reduces risk of bacille Calmette- Guérin immune reconstitution adenitis
SETTING: Two centres in Soweto and Cape Town, South Africa. OBJECTIVE: To assess the effects of timing of initiation of antiretroviral treatment (ART) and other factors on the risk of bacille Calmette-Guérin (BCG) related ...