Now showing items 31-40 of 71
Use of Studded Polyflex™ Stents in Patients with Neoplastic Obstructions of the Central Airways
Background: The Polyflex™ is a commercially available silastic airway stent with proven efficacy. Due to a smooth outer surface its anchorage in the airway wall is superficial which may lead to stent migration. Objective: ...
Safety and yield of ultrasound-assisted transthoracic biopsy performed by pulmonologists
Background: Transthoracic ultrasound (US) has gained popularity as a tool for visualizing pleural effusions and assisting thoracentesis or chest drain placement. In the absence of effusion, US just as well demonstrates ...
Proportion of tuberculosis transmission that takes place in households in a high-incidence area
The prevalence of infection among household contacts of people with tuberculosis is high. This information frequently guides active case finding. We analysed DNA fingerprints of Mycobacterium tuberculosis from 765 tuberculosis ...
Depression and anxiety in the developing world: Is it time to medicalise the suffering?
[No abstract available]
Vascular endothelial growth factor and blood-brain barrier disruption in tuberculous meningitis
Background: Tuberculous meningitis (TBM) is characterized by disruption of the blood-brain barrier (BBB), cerebral edema and increased intracranial pressure (ICP). Vascular endothelial growth factor (VEGF) is a potent ...
Resistant Mycobacterium bovis Bacillus Calmette-Guérin Disease: Implications for Management of Bacillus Calmette-Guérin Disease in Human Immunodeficiency Virus-Infected Children
Guidelines for the diagnosis and management of Bacillus Calmette-Guérin (BCG) disease in children are lacking, and there are limited data on drug resistance of Mycobacterium bovis BCG. A 6-month-old HIV-infected infant ...
Clonal expansion of a globally disseminated lineage of Mycobacterium tuberculosis with low IS6110 copy numbers
Knowledge of the clonal expansion of Mycobacterium tuberculosis and accurate identification of predominant evolutionary lineages in this species remain limited, especially with regard to low-IS6110-copy-number strains. In ...
Genomic characterization of an endemic Mycobacterium tuberculosis strain: Evolutionary and epidemiologic implications
In a study of 302 Mycobacterium tuberculosis clinical isolates from the low-incidence Canadian-born population of Quebec, we characterized a large endemic strain family by using genomic deletions. The DS6Quebec deleted ...
Genotypic and Phenotypic Characterization of Drug-Resistant Mycobacterium tuberculosis Isolates from Rural Districts of the Western Cape Province of South Africa
Genotypic and phenotypic analysis of drug-resistant Mycobacterium tuberculosis isolates from the Western Cape Province of South Africa showed that drug resistance is widespread and recently transmitted. Multidrug-resistant ...
Transposition rates of Mycobacterium tuberculosis IS6110 restriction fragment length polymorphism patterns
To determine the rate at which IS1160 restriction fragment length polymorphism (RFLP) patterns in Mycobacterium tuberculosis change over time, we applied a smooth nonparametric survival model to several data sets, including ...