Now showing items 21-30 of 508
Virologic failure and second-line antiretroviral therapy in children in South Africa-the IeDEA Southern Africa collaboration
Background: With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determinants of virologic ...
Combined antiretroviral treatment initiation during hospitalization: Outcomes in south african adults
[No abstract available]
Intracytoplasmic sperm injection with testicular spermatozoa in men with azoospermia
Purpose: The aim of the study was to gain an insight into the optimal management of the infertile couple with the husband suffering from azoospermia. Methods: One hundred and forty-two intracytoplasmic sperm injection ...
Evaluating the equivalence of clomiphene citrate with and without metformin in ovulation induction in PCOS patients
Objective: To evaluate the benefit of Metfomin added to Clomiphene Citrate in a primary ovulation induction protocol in PCOS patients Design: Prospective randomised controlled study Setting: Tygerberg Academic Hospital, ...
Relationship between Human Sperm Morphology and Acrosomal Function
Purpose: In this study, we investigated the relationship between functionality of the acrosome and sperm morphology. Methods: Acrosome reaction (AR) was separately determined in live and dead sperm and in those with normal, ...
Physiological induction of the acrosome reaction in human sperm: Validation of a microassay using minimal volumes of solubilized, homologous zona pellucida
Purpose: To develop a method that could accommodate microvolumes of solubilized human zona pellucida (ZP) and sperm for assessing the induction of the acrosome reaction. Methods: A microassay using 1 μl of 2.5, 1.25, 0.6, ...
An intracytoplasmic sperm injection pregnancy with a globozoospermic male
[No abstract available]
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures a prospective, controlled, randomized study of four hundred and fifty patients
Background: The treatment of open fractures of the tibial shaft is often complicated by delayed union and non-union. The objective of this study was to evaluate the safety and efficacy of the use of recombinant human bone ...
Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid
Aim: Little is known about pyridoxine nutriture of children treated with isoniazid (INH) regimens. This study documents plasma pyridoxal 5′-phosphate (PLP) concentrations in children, HIV-infected and HIV-uninfected, ...
Seasonal influence on the admittance of pre-eclampsia patients in Tygerberg hospital
Background. Previous studies suggest that the occurrence of pre-eclampsia is seasonally distributed. This retrospective study aims to determine whether there is a seasonal variation in the number of admissions and the ...