Now showing items 21-30 of 62
Risk of invasive cancer of the cervix in relation to the use of injectable progestogen contraceptives and combined estrogen/progestogen oral contraceptives (South Africa)
Background: Cervical cancer is caused by specific types of the human papilloma virus (HPV), but not all infected women develop cancer. It has been hypothesized that hormonal contraceptives may potentiate the oncogenicity ...
National surveillance programme on susceptibility patterns of respiratory pathogens in South Africa: Moxifloxacin compared with eight other antimicrobial agents
Aims: The susceptibility patterns of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Klebsiella pneumoniae, and Streptococcus pyogenes isolated from specimens submitted to 12 private laboratories ...
The hereditary adult-onset ataxias in South Africa
There is little data on the spectrum and frequencies of the autosomal dominant spinocerebellar ataxias (SCAs) from the African continent. We undertook a large prospective population-based study over a 10-year period in ...
Chromosome painting in the African four-striped mouse Rhabdomys pumilio: Detection of possible murid specific contiguous segment combinations
Fluorescence in-situ hybridization was used to construct a comparative chromosome map between the laboratory mouse, Mus musculus and the African four-striped mouse, Rhabdomys pumilio. A high degree of homology between the ...
A randomised, double-blind placebo-controlled trial of ascorbic acid supplementation for the prevention of preterm labour
In a previous study from this institution, patients at high risk for preterm labour were screened for the presence of bacterial vaginosis (BV). When BV was present, they were randomised to receive either treatment ...
Pre-eclampsia, mechanical heart valve prosthesis and prematurity
[No abstract available]
Molecular characteristics of human immunodeficiency virus type 1 subtype C viruses from Kwazulu-Natal, South Africa: Implications for vaccine and antiretroviral control strategies
The KwaZulu-Natal region of South Africa is experiencing an explosive outbreak of human immunodeficiency virus type 1 (HIV-1) subtype C infections. Understanding the genetic diversity of C viruses and the biological ...
Neurologic outcome after penetrating extracranial arterial trauma
Purpose: We undertook this study to determine factors that adversely affect outcome in patients with penetrating injury to the extracranial cerebral vasculature. Patients and Methods: Medical records were reviewed for all ...
Variability at human immunodeficiency virus type 1 subtype C protease cleavage sites: An indication of viral fitness?
Naturally occurring polymorphisms in the protease of human immunodeficiency virus type 1 (HIV-1) subtype C would be expected to lead to adaptive (compensatory) changes in protease cleavage sites. To test this hypothesis, ...
Long term survival of children with burkitt lymphoma in Malawi after cyclophosphamide monotherapy
Background. Between 1991 and 1997, limited funding at times restricted available treatment for children with Burkitt lymphoma (BL) to cyclophosphamide (CPM) monotherapy at Lilongwe Central Hospital, Malawi. Our objective ...