Now showing items 11-20 of 214
Physiological induction of the acrosome reaction in human sperm: Validation of a microassay using minimal volumes of solubilized, homologous zona pellucida
Purpose: To develop a method that could accommodate microvolumes of solubilized human zona pellucida (ZP) and sperm for assessing the induction of the acrosome reaction. Methods: A microassay using 1 μl of 2.5, 1.25, 0.6, ...
An intracytoplasmic sperm injection pregnancy with a globozoospermic male
[No abstract available]
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures a prospective, controlled, randomized study of four hundred and fifty patients
Background: The treatment of open fractures of the tibial shaft is often complicated by delayed union and non-union. The objective of this study was to evaluate the safety and efficacy of the use of recombinant human bone ...
Traumatic dislocation of the atlanto-occipital joint
We present four patients who had sustained a traumatic dislocation of the atlanto-occipital joint. The diagnosis was initially missed in two patients. One patient, who was neurologically intact, was treated non-operatively. ...
Childhood drug-resistant tuberculosis in the Western Cape Province of South Africa
Aim: Continued surveillance of drug resistance amongst children presenting with culture-confirmed tuberculosis to a tertiary care hospital and to community clinics. Methods: Drug susceptibility testing for isoniazid and ...
Nosocomial transmission of Mycobacterium tuberculosis in kangaroo mother care units: A risk in tuberculosis-endemic areas
Background and aim: Kangaroo mother care (KMC) has become the standard of care for low-risk preterm babies born in developing countries. However, the potential risk of nosocomial transmission of Mycobacterium tuberculosis ...
HIV risk exposure among South African children in public health facilities
The study investigates the risk exposure to HIV infection among South African children aged 2-9 years served by public health services. Together with their biological mothers, 3471 children and were recruited from inpatient ...
Change in co-receptor usage of current South African HIV-1 subtype C primary isolates
Phenotypic analysis was performed on 13 HIV-1 strains isolated between 2000 and 2001. Syncytium-inducing and non-syncytium-inducing subtype C viruses were found, most of which used more than one co-receptor. For the first ...
Phase II trial of ZD0473 as second-line therapy in mesothelioma
A phase II, open-label, non-comparative, multicentre trial of the platinum analogue ZD0473 as second-line therapy for pleural mesothelioma has been completed. The objectives were to evaluate the activity and tolerability ...