Now showing items 11-20 of 306
Tuberculosis exposure in HIV-exposed infants in a high-prevalence setting
Exposure to TB was quantified by screening human immunodeficiency virus (HIV) exposed infants aged 3-4 months for an isoniazid prophylaxis study where tuberculosis (TB) exposure excluded enrolment. Seventy-seven (10.1%, ...
Cytokine production in patients with tuberculous pericarditis
SETTING: An academic hospital in the Western Cape, South Africa. OBJECTIVE: To evaluate cytokine production (interferon-gamma [IFN-γ], interleukin-1 [IL-1], interleukin-2 [IL-2], interleukin-6 [IL-6], interleukin-10 [IL-10], ...
Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa
Background: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in children retained in care and in all ...
Virologic failure and second-line antiretroviral therapy in children in South Africa-the IeDEA Southern Africa collaboration
Background: With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determinants of virologic ...
Intracytoplasmic sperm injection with testicular spermatozoa in men with azoospermia
Purpose: The aim of the study was to gain an insight into the optimal management of the infertile couple with the husband suffering from azoospermia. Methods: One hundred and forty-two intracytoplasmic sperm injection ...
Relationship between Human Sperm Morphology and Acrosomal Function
Purpose: In this study, we investigated the relationship between functionality of the acrosome and sperm morphology. Methods: Acrosome reaction (AR) was separately determined in live and dead sperm and in those with normal, ...
Physiological induction of the acrosome reaction in human sperm: Validation of a microassay using minimal volumes of solubilized, homologous zona pellucida
Purpose: To develop a method that could accommodate microvolumes of solubilized human zona pellucida (ZP) and sperm for assessing the induction of the acrosome reaction. Methods: A microassay using 1 μl of 2.5, 1.25, 0.6, ...
An intracytoplasmic sperm injection pregnancy with a globozoospermic male
[No abstract available]
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures a prospective, controlled, randomized study of four hundred and fifty patients
Background: The treatment of open fractures of the tibial shaft is often complicated by delayed union and non-union. The objective of this study was to evaluate the safety and efficacy of the use of recombinant human bone ...
Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid
Aim: Little is known about pyridoxine nutriture of children treated with isoniazid (INH) regimens. This study documents plasma pyridoxal 5′-phosphate (PLP) concentrations in children, HIV-infected and HIV-uninfected, ...