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Now showing items 11-20 of 45

The optimal dosage of ketanserin for patients with severe hypertension in pregnancy

Van Schie D.L.; De Jeu R.M.; Steyn D.Wilhelm; Odendaal H.J.; Van Geijn H.P. (2002)

Objective: To establish the optimal dosage of ketanserin in the treatment of severe hypertension in pregnancy. Study design: A double blind prospective randomised controlled trail, comparing 10mg ketanserin given as ...

A pilot study of deep sclerectomy with implantation of chromic suture material as a collagen implant: Medium-term results

Wevill M.T.; Meyer D.; Van Aswegen E. (2005)

Aims: A pilot study of the safety and efficacy of deep sclerectomy with a chromic suture implant (DSCI) for open angle glaucoma. Methods: This prospective trial involved 23 eyes of 16 consecutive patients with uncontrolled ...

No clinical benefit of adding cisapride to pantoprazole for treatment of gastro-oesophageal reflux disease

Van Rensburg C.J.; Bardhan K.D. (2001)

Objective Although a proton pump inhibitor (PPI) and a prokinetic drug are often combined for the medical treatment of gastro-oesophageal reflux disease (GORD), there are few well-conducted clinical studies on the efficacy ...

Oral ibandronate for the treatment of metastatic bone disease in breast cancer: Efficacy and safety results from a randomized, double-blind, placebo-controlled trial

Tripathy, D.; Lichinitzer, M.; Lazarev, A.; MacLachlan, S. A.; Apffelstaedt, J.; Budde, M.; Bergstrom, B.; Abdi, E.; Abramson, N.; Baker, T. M.; Kirkegaard, L. W.; Schmidt, J. R.; Bell, D.; Bell, R.; Belt, R. J.; Bernstein, J. I.; Just, R. G.; Burningham, R. A.; Trafficante, B.; Caggiano, V.; Cartwright, T.; Chernozemsky, I. N.; Clingan, P.; Conkling, P.; Craig, J. B.; Grosbach, A. B.; Decker, D.; Dickman, E.; Duga, Jr. W.; Dunlap, W.; Eisenberg, P. D.; Ellerton, J.; Ettinger, M.; Ey, F.; Falkson, G.; Falkson, C.; Fink, K.; Fleagle, J.; Forlenza, T.; Gorbunova, V. A.; Gross, G. E.; Grotes, T.; Grygiel, J.; Gudgeon, A.; Werner, I. D.; Hacking, D.; Harrer, G. W.; Harvey, V.; Hirsch, R.; Koletsky, A.; Jordaan, J. P.; Cash, D. K.; Khasanov, R. Sh.; LaFata, J. A.; Lafollette, S.; Koshla, P.; Landers, G.; Lebos, H. C.; Wade, J. L.; Lowenthal, T.; Lyons, R.; McLachlan, S. A.; Murray, R.; Perez, D.; Phadke, K.; Rapoport, B.; Rausch, P. G.; Robinson, B.; Sarna, G.; Saven, A.; Schwartz, M.; Semiglazov, V. F.; Stewart, J.; Sunderland, K.; Thomas, L.; Vogel, C. L.; Martinez Rio, M.; Vorobiof, D. A.; Wilks, S.; Woolley, P. (2004)

Background: We report the first results of a randomized trial assessing a new oral aminobisphosphonate, ibandronate, in patients with bone metastases from breast cancer. Patients and methods: Patients (n = 435) received ...

Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: A phase III, double-blind, comparative trial

Rosen L.S.; Gordon D.; Kaminski M.; Howell A.; Belch A.; Mackey J.; Apffelstaedt J.; Hussein M.; Coleman R.E.; Reitsma D.J.; Seaman J.J.; Chen B.-L.; Ambros Y. (2001)

PURPOSE: Zoledronic acid, a new and more potent bisphosphonate, was compared with pamidronate, the current standard treatment for patients with osteolytic or mixed bone metastases/lesions. PATIENTS AND METHODS: A total of ...

Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis

Appel, G. B.; Contreras, G.; Dooley, M. A.; Ginzler, E. M.; Isenberg, D.; Jayne, D.; Li, L-S.; Mysler, E.; Sanchez-Guerrero, J.; Solomons, N.; Wofsy, D.; Abud, C.; Adler, S.; Alarcon, G.; Albuquerque, E.; Almeida, F.; Alvarellos, A.; Appel, G.; Avila, H.; Blume, C.; Boletis, I.; Bonnardeaux, A.; Braun, A.; Buyon, J.; Cervera, R.; Chen, N.; Chen, S.; Da Costa, A. G.; Davids, M. R.; D'Cruz, D.; De Ramon, E.; Deodhar, A.; Doria, A.; Dussol, B.; Emery, P.; Fiechtner, J.; Floege, J.; Fragoso-Loyo, H.; Furie, R.; Ghazalli, R.; Ghossein, C.; Gilkeson, G.; Ginzler, E.; Gordon, C.; Grossman, J.; Gu, J.; Guillevin, L.; Hatron, P. Y.; Herrera, G.; Hiepe, F.; Houssiau, F.; Hubscher, O.; Hura, C.; Kaplan, J.; Kirsztajn, G.; Kiss, E.; Kutty, G. A.; Laville, M.; Lazaro, M.; Lenz, O.; Li, L.; Lightstone, L.; Lim, S.; Malaise, M.; Manzi, S.; Marcos, J.; Meyer, O.; Monge, P.; Naicker, S.; Neal, N.; Neuwelt, M.; Nicholls, K.; Olsen, N.; Ordi-Ros, J.; Ostrov, B.; Pestana, M.; Petri, M.; Pokorny, G.; Pourrat, J.; Qian, J.; Radhakrishnan, J.; Rovin, B.; Roman, J. S.; Shanahan, J.; Shergy, W.; Skopouli, F.; Spindler, A.; Striebich, C.; Sundel, R.; Swanepoel, C.; Si, Y. T.; Tate, G.; Tesar, V.; Tikly, M.; Wang, H.; Yahya, R.; Yu, X.; Zhang, F.; Zoruba, D. (2009)

Recent studies have suggested that mycophenolate mofetil (MMF) may offer advantages over intravenous cyclophosphamide (IVC) for the treatment of lupus nephritis, but these therapies have not been compared in an international ...

Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: Two parallel randomized, placebo-controlled, double-blind clinical trials

Boffard K.D.; Riou B.; Warren B.; Choong P.I.T.; Rizoli S.; Rossaint R.; Axelsen M.; Kluger Y.; Champion H.R.; Lucas C.; Thompson E.; Ross S.; Jurkovich G.J.; Lynn M.; Pitts L.; Croce M.A. (2005)

Background: Uncontrolled bleeding is a leading cause of death in trauma. Two randomized, placebo-controlled, double-blind trials (one in blunt trauma and one in penetrating trauma) were conducted simultaneously to evaluate ...

Safety of pleurodesis with talc poudrage in malignant pleural effusion: a prospective cohort study

Janssen J.P.; Collier G.; Astoul P.; Tassi G.F.; Noppen M.; Rodriguez-Panadero F.; Loddenkemper R.; Herth F.J.; Gasparini S.; Marquette C.H.; Becke B.; Froudarakis M.E.; Driesen P.; Bolliger C.T.; Tschopp J.-M. (2007)

Background: Talc is the most effective chemical pleurodesis agent for patients with malignant pleural effusion. However, concerns have arisen about the safety of intrapleural application of talc, after reports of development ...

Prediction of functional reserves after lung resection: Comparison between quantitative computed tomography, scintigraphy, and anatomy

Bolliger C.T.; Guckel C.; Engel H.; Stohr S.; Wyser C.P.; Schoetzau A.; Habicht J.; Soler M.; Tamm M.; Perruchoud A.P. (2002)

Background and Objectives: We prospectively compared five techniques to estimate predicted postoperative function (ppo F) after lung resection: recently proposed quantitative CT scans (CT), perfusion scans (Q), and three ...

Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia

Kastelein J.J.P.; Van Leuven S.I.; Burgess L.; Evans G.W.; Kuivenhoven J.A.; Barter P.J.; Revkin J.H.; Grobbee D.E.; Riley W.A.; Shear C.L.; Duggan W.T.; Bots M.L. (2007)

Background: Torcetrapib, an inhibitor of cholesteryl ester transfer protein, may reduce atherosclerotic vascular disease by increasing levels of high-density lipoprotein (HDL) cholesterol. Methods: A total of 850 patients ...