Now showing items 11-20 of 24
Safety of pleurodesis with talc poudrage in malignant pleural effusion: a prospective cohort study
Background: Talc is the most effective chemical pleurodesis agent for patients with malignant pleural effusion. However, concerns have arisen about the safety of intrapleural application of talc, after reports of development ...
Roflumilast, a phosphodiesterase 4 inhibitor, reduces airway hyperresponsiveness after allergen challenge
Background: Roflumilast, an oral, once-daily phosphodiesterase 4 inhibitor, is currently in clinical development for the treatment of asthma. Objectives: This pilot study examined the effect of roflumilast on allergen-induced ...
A nicotine mouth spray for smoking cessation: A pilot study of preference, safety and efficacy
Background: Various formulations of nicotine replacement therapy are commercially available. Objectives: It was the aim of this study to test preference, safety and efficacy of a new nicotine mouth spray (1 mg/actuation; ...
Atypical pneumonia - An uncommon presentation of a well-known disease
[No abstract available]
Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia
Background: Torcetrapib, an inhibitor of cholesteryl ester transfer protein, may reduce atherosclerotic vascular disease by increasing levels of high-density lipoprotein (HDL) cholesterol. Methods: A total of 850 patients ...
An assessment of preliminary food-based dietary guidelines for infants 6-12 months of age in the Little Karoo area of the Western Cape Province of South Africa
Objective: This study aimed to assess mother's/caregiver's understanding, practical application and cultural acceptability of a preliminary set of South African food-based dietary guidelines (FBDGs) for children aged 6-12 ...
Bicalutamide (Casodex) 150 mg plus standard care in early non-metastatic prostate cancer: Results from Early Prostate Cancer Trial 24 at a median 7 years' follow-up
Trial 24, one of three ongoing trials in the Early Prostate Cancer programme, is evaluating the efficacy and tolerability of bicalutamide (Casodex) 150 mg following standard care (radiotherapy, radical prostatectomy or ...
Efficacy, safety and early response of paliperidone extended-release tablets (paliperidone ER): Results of a 6-week, randomized, placebo-controlled study
Background: Paliperidone extended-release tablet (paliperidone ER) is an oral psychotropic agent developed for schizophrenia treatment. Paliperidone (9-OH-risperidone, metabolite of risperidone), when used with OROS ...
Changes in echogenicity in the fetal brain: A prevalence study in fetuses at risk for preterm delivery
Objectives: To study the incidence of echodensities in the periventricular white matter, ventricular system, basal ganglia and thalamus of the brain in fetuses at risk for preterm delivery. Methods: This was a prospective ...
FAME 3: A novel form of progressive myoclonus and epilepsy
BACKGROUND: Familial adult myoclonic epilepsy (FAME) is associated with myoclonus, tremor, and rare seizures, and is a nonprogressive disorder linked to the FAME 1 locus. A similar disorder has been linked to the FAME 2 ...