Now showing items 1-10 of 20
Maternal HIV infection and antibody responses against vaccine-preventable diseases in uninfected infants
Context: Altered immune responses might contribute to the high morbidity and mortality observed in human immunodeficiency virus (HIV)-exposed uninfected infants. Objective: To study the association of maternal HIV infection ...
Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa
Background: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in children retained in care and in all ...
Virologic failure and second-line antiretroviral therapy in children in South Africa-the IeDEA Southern Africa collaboration
Background: With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determinants of virologic ...
Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid
Aim: Little is known about pyridoxine nutriture of children treated with isoniazid (INH) regimens. This study documents plasma pyridoxal 5′-phosphate (PLP) concentrations in children, HIV-infected and HIV-uninfected, ...
Prioritising prevention strategies for patients in antiretroviral treatment programmes in resource-limited settings
Expanded access to antiretroviral therapy (ART) offers opportunities to strengthen HIV prevention in resource-limited settings. We invited 27 ART programmes from urban settings in Africa, Asia and South America to participate ...
Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007
Objective: Little is known about the temporal impact of the rapid scale-up of large antiretroviral therapy (ART) services on programme outcomes. We describe patient outcomes [mortality, loss-to-follow-up (LTFU) and retention] ...
Tuberculosis in women and children
[No abstract available]
Evaluation of paradoxical TB-associated IRIS with the use of standardized case definitions for resource-limited settings
Objective: Standardized case definitions have recently been proposed by the International Network for the Study of HIV-associated immune reconstitution inflammatory syndrome (INSHI; [IRIS]) for use in resource-limited ...
HIV/AIDS and disability organisations in South Africa
Despite the seriousness of the HIV epidemic globally, and in South Africa in particular, little is known about how HIV/AIDS affects disabled people. One important and little explored area is the role that organisations ...
Symptoms of depression and anxiety among a sample of South African patients living with HIV
Little systematic research has been conducted on the extent of psychiatric disorders among South African patients in general, and among patients living with HIV in particular. The present study reports on a survey conducted ...