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Cytokine production in patients with tuberculous pericarditis

Burgess L.J.; Reuter H.; Carstens M.E.; Taljaard J.J.F.; Doubell A.F. (2002)

SETTING: An academic hospital in the Western Cape, South Africa. OBJECTIVE: To evaluate cytokine production (interferon-gamma [IFN-γ], interleukin-1 [IL-1], interleukin-2 [IL-2], interleukin-6 [IL-6], interleukin-10 [IL-10], ...

Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures a prospective, controlled, randomized study of four hundred and fifty patients

Govender S.; Csimma C.; Genant H.K.; Valentin-Opran A.; Amit Y.; Arbel R.; Aro H.; Atar D.; Bishay M.; Borner M.G.; Chiron P.; Choong P.; Cinats J.; Courtenay B.; Feibel R.; Geulette B.; Govender S.; Gravel C.; Haas N.; Raschke M.; Hammacher E.; Van der Velde D.; Hardy P.; Holt M.; Josten C.; Ketterl R.L.; Lindeque B.; Lob G.; Mathevon H.; McCoy G.; Marsh D.; Miller R.; Munting E.; Oevre S.; Nordsletten L.; Patel A.; Pohl A.; Rennie W.; Reynders P.; Rommens P.M.; Rondia J.; Rossouw W.C.; Daneel P.J.; Ruff S.; Ruter A.; Santavirtal S.; Schidhauer T.A.; Gekle C.; Schnettler R.; Segal D.; Seiler H.; Snowdowne R.B.; Stapert J.; Taglang G.; Verdonik R.; Vogels L.; Weckbach A.; Wentzensen A.; Wisriewsk T. (2002)

Background: The treatment of open fractures of the tibial shaft is often complicated by delayed union and non-union. The objective of this study was to evaluate the safety and efficacy of the use of recombinant human bone ...

Phase II trial of ZD0473 as second-line therapy in mesothelioma

Giaccone G.; O'Brien M.E.R.; Byrne M.J.; Bard M.; Kaukel E.; Smit B. (2002)

A phase II, open-label, non-comparative, multicentre trial of the platinum analogue ZD0473 as second-line therapy for pleural mesothelioma has been completed. The objectives were to evaluate the activity and tolerability ...

Intrauterine insemination: A systematic review on determinants of success

Duran H.E.; Morshedi M.; Kruger T.; Oehninger S. (2002)

Intrauterine insemination (IUI) is a frequently indicated therapeutic modality in infertility. Here, a systematic review of the literature was performed to examine the current status of clinical and laboratory methodologies ...

Long-term follow up of childhood tuberculous meningitis

Schoeman J.; Wait J.; Burger Hons M.; Van Zyl F.; Fertig G.; Van Janse Rensburg A.; Springer P.; Donald P. (2002)

The purpose of the present study was to determine the long-term outcome of 76 children (40 females and 36 males) diagnosed and treated with modern antituberculosis drugs. The median age of the children on admission was ...

Lymphedema-lymphangiectasia-mental retardation (Hennekam) syndrome: A review

Van Balkom I.D.C.; Alders M.; Allanson J.; Bellini C.; Frank U.; De Jong G.; Kolbe I.; Lacombe D.; Rockson S.; Rowe P.; Wijburg F.; Hennekam R.C.M. (2002)

The Hennekam syndrome is an infrequently reported heritable entity characterized by lymphedema, lymphangiectasia, and developmental delay. Here we add an additional 8 patients, and compare their findings to the 16 cases ...

HHV-8 subtypes in South Africa: Identification of a case suggesting a novel B variant

Treurnicht F.K.; Engelbrecht S.; Taylor M.B.; Schneider J.W.; Van Rensburg E.J. (2002)

Human herpesvirus 8 (HHV-8) has been identified as the causative agent for all forms of Kaposi's sarcoma and is also associated with the development of body cavity- based B-cell lymphomas and multicentric Castleman's ...

Tuberculosis meningitis and attention deficit hyperactivity disorder in children

Wait J.W.V.; Stanton L.; Schoeman J.F. (2002)

The purpose of this study was to investigate the prevalence of attention deficit hyperactivity disorder (ADHD) in children who recovered from tuberculous meningitis (TBM) as part of an ongoing TBM research project. During ...

Prediction of functional reserves after lung resection: Comparison between quantitative computed tomography, scintigraphy, and anatomy

Bolliger C.T.; Guckel C.; Engel H.; Stohr S.; Wyser C.P.; Schoetzau A.; Habicht J.; Soler M.; Tamm M.; Perruchoud A.P. (2002)

Background and Objectives: We prospectively compared five techniques to estimate predicted postoperative function (ppo F) after lung resection: recently proposed quantitative CT scans (CT), perfusion scans (Q), and three ...

Defective sperm decondensation: A cause for fertilization failure

Esterhuizen A.D.; Franken D.R.; Becker P.J.; Lourens J.G.H.; Muller I.I.; Van Rooyen L.H. (2002)

The study aimed to evaluate the role of chromatin packaging (CMA3 staining), sperm morphology during sperm-zona binding, sperm decondensation and the presence of polar bodies in oocytes that failed in vitro fertilization ...