Now showing items 1-10 of 18
Esomeprazole 40 mg administered intravenously has similar safety and efficacy profiles to the oral formulation in patients with erosive esophagitis
Background/Aims: An intravenous formulation of esomeprazole has been developed for use in patients where oral administration is not appropriate. This study evaluated safety after 1 and 4 weeks, and efficacy after 4 weeks' ...
Can CT predict the level of CSF block in tuberculous hydrocephalus?
Introduction: Treatment of obstructive hydrocephalus in children with tuberculous meningitis (TBM) depends on the level of the cerebrospinal fluid (CSF) block. Air-encephalography is regarded as the gold standard for ...
Efficacy and safety of pantoprazole versus ranitidine in the treatment of patients with symptomatic gastroesophageal reflux disease
Background/Aim: Gastroesophageal reflux disease (GERD) is a prevalent disease associated with a high symptom burden and a reduced quality of life. This multicenter, randomized, double-blind study compared relief from key ...
Intrapleural streptokinase for empyema and complicated parapneumonic effusions
We conducted a single-center, randomized, placebo-controlled trial to determine whether streptokinase instillations adjunctive to chest tube drainage reduce the need for surgery and improve outcome in patients with pleural ...
Oral ibandronate for the treatment of metastatic bone disease in breast cancer: Efficacy and safety results from a randomized, double-blind, placebo-controlled trial
Background: We report the first results of a randomized trial assessing a new oral aminobisphosphonate, ibandronate, in patients with bone metastases from breast cancer. Patients and methods: Patients (n = 435) received ...
Expression, purification, biochemical and pharmacological characterization of a recombinant aprotinin variant
Aprotinin (CAS 9087-70-1) is known as a potent inhibitor of serine proteases such as trypsin, plasmin, tissue and plasma kallikrein. In this study, an aprotinin variant was designed by means of rationale mutagenesis that ...
Collection of fetal cells in cervical secretions without ultrasound guidance
[No abstract available]
Comparison of a new desktop spirometer (Spirospec) with a laboratory spirometer in a respiratory out-patient clinic
BACKGROUND: The performance of spirometers is often evaluated under ideal conditions with computergenerated waveforms or in vivo testing with healthy subjects. Real-life conditions are less ideal because of comorbidities, ...
Vascular endothelial growth factor and blood-brain barrier disruption in tuberculous meningitis
Background: Tuberculous meningitis (TBM) is characterized by disruption of the blood-brain barrier (BBB), cerebral edema and increased intracranial pressure (ICP). Vascular endothelial growth factor (VEGF) is a potent ...