Now showing items 1-10 of 852
Proximal renal tubular acidosis in pregnancy: A case report and literature review
Renal tubular acidosis is usually associated with chronic renal conditions and is rarely encountered in pregnancy. It may be inherited causing osteomalacia and rickets in children or acquired following autoimmune diseases ...
Selective lysis of erythrocytes infected with the trophozoite stage of Plasmodium falciparum by polyene macrolide antibiotics
The continuous increase in strains of the human malaria parasite Plasmodium falciparum resistant to most front-line antimalarial compounds is reason for grave clinical concern. The search for new drugs led us to investigate ...
Erythrocyte membrane fatty acids in patients with multiple sclerosis
Background: Reports on fatty acids levels in multiple sclerosis remain inconclusive. Objective: To determine the erythrocyte membrane fatty acid levels in multiple sclerosis patients and correlate with Kurtzke Expanded ...
Fatal hepatitis B infection despite immunization in an HIV-infected infant: A possible case of vaccine failure and immune reconstitution inflammatory syndrome
We report a case of hepatitis B immune reconstitution inflammatory syndrome in an 8-month-old girl with Mycobacterium tuberculosis complex and human immunodeficiency virus (HIV) co-infection. In resource-constrained ...
Lymphoma - The immune system in disarray Theme for the 11th Congress of the South African Lymphoma Study Group meeting
[No abstract available]
Effects of myo-Inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cellsEffects of myo-Inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cells
myo-Inositol (mI) is a key metabolic precursor to the phospoinositide (PI) metabolic pathway as a key component of central G-protein coupled receptor signaling systems, including several subtypes of adrenergic, cholinergic, ...
Use of novel proteosome inhibitors as a therapeutic strategy in lymphomas current experience and emerging concepts
Precedent from preclinical experiments coupled with two pivotal phase 2 studies in myeloma has focused attention on a potential role for ubiquitin-proteasome pathway in modulating a number of events that occur commonly in ...
The value of ultrasound examination of the lungs in predicting bronchopulmonary dysplasia
Background: Bronchopulmonary dysplasia (BPD) is one of the most serious complications of neonatal mechanical ventilation. Early diagnosis may influence treatment options such as early steroid administration. Objective: To ...
Localized basal meningeal enhancement in tuberculous meningitis
Background: Focal basal meningeal enhancement may produce a confusing CT picture in children with suspected tuberculous meningitis (TBM). Objective: To demonstrate the incidence, distribution and appearance of localized ...
Evaluating the BED capture enzyme immunoassay to estimate HIV incidence among adults in three countries in sub-Saharan Africa
Serological assays for estimating HIV-1 incidence are prone to misclassification, limiting the accuracy of the incidence estimate. Adjustment factors have been developed and recommended for estimating assay-based HIV-1 ...