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Use of novel proteosome inhibitors as a therapeutic strategy in lymphomas current experience and emerging concepts

Abayomi, E. A.; Sissolak, G.; Jacobs, P. (2007)

Precedent from preclinical experiments coupled with two pivotal phase 2 studies in myeloma has focused attention on a potential role for ubiquitin-proteasome pathway in modulating a number of events that occur commonly in ...

Effects of myo-Inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cellsEffects of myo-Inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cells

Brink, C. B.; Viljoen, S. L.; De Kock, S. E.; Stein, D. J.; Harvey, B. H.; Brink, C. B.; Viljoen, S. L.; De Kock, S. E.; Stein, D. J.; Harvey, B. H. (2004)

myo-Inositol (mI) is a key metabolic precursor to the phospoinositide (PI) metabolic pathway as a key component of central G-protein coupled receptor signaling systems, including several subtypes of adrenergic, cholinergic, ...

Microscopic studies on the Aspergillus flavus infected kernels of commercial peanuts in Georgia

Achar, P. N.; Hermetz, K.; Rao, S.; Apkarian, R.; Taylor, J. (2009)

This article describes the use of microscopy to prove the presence of the aflatoxin producing pathogen, Aspergillus flavus Link ex Fries in commercially available edible peanuts in Georgia. Light microscopy in combination ...

The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for children at 18 months

Duley, L.; Farrell, B.; Armstrong, N.; Spark, P.; Roberts, B.; Smyth, R.; Tivnan, M.; Laws, A.; Corfield, N.; Salte, A.; Thorn, L.; Altman, D.; Yu, L. M.; Abalos, E.; Carroli, B.; Dellepiane, L.; Duarte, M.; Fernandez, H.; Giordano, D.; Clarke, M.; Gray, A.; Hey, E.; Neilson, J.; Simon, J.; Doyle, L.; Kelly, T.; Squires, J.; Collins, R.; Karaoglou, A.; Lilford, R.; Moodley, J.; Robson, S.; Roberts, I.; Rubin, P.; Thornton J.; Twaddle, S.; Villar, J.; Walker, I.; Watkins, C.; Bimbashi, A.; Demalia, E.; Gliozheni ,O.; Shpata, A.; Karolinski, A.; Lamas, M.; Pesaresi, M.; Wainer, V.; Barbato, W.; Paciocco, M.; Bertin, M.; Boiza, E.; Castaldi, J.; Partida, Y.; Arias, C.; Farri, M.; Kerz, G.; Aguirre, J.; De Sagastizabal, M.; Falcone, R.; Morales, E.; Carroli, G.; Krupitzky, S.; Lopez, S.; Palermo, M.; Montes, Varela D.; Delprato, H.; Camusso, H.; Curioni, M.; Ludmer, E.; Brandi, R.; Martin, R.; Mesas, W.; Taralli, R.; Lezaola, M.; Morosini, M.; Andina, E.; Bernal, L.; Estiu, M.; Ulens, E.; Ortiz De Speranza, B.; Peyrano, A.; Damiano, M.; Saumench, C.; Horn, J.; Pritchard, M.; Smith-Orr, V.; Wilson, M.; Lawrence, A.; Watson, D.; Crowther, C.; Paynter, J.; Ashrafunnessa,; Mannan, M.; Shahidullah, M.; Shamsuddin, L.; Barros, Santos C.; Freire, S.; Melo, E.; Cobo, E.; Jaramillo, E.; Cardozo, C.; Fandino, N.; Gaitan, H.; Montano, L.; Lozano, J.; Rojas, M.; Breto, Garcia A.; Fuentes, Ramirez A.; Garcia, Miras R.; Sampera, S.; Farnot, U.; Gomez, E.; Rojas, G.; Valdes, R.; Abd El-Kreem, H.; Al-Hussaini, T.; Hammad, E.; Danso, K.; Kwapong, E.; Ofosu-Barko, E.; Padmini, Jasper M.; Peedicayil, A.; Regi, A.; Sharma, R.; Chauhan, A.; Raut, V.; Udani, R.; Batra, S.; Muthal-Rathore, A.; Ramji, S.; Zutshi, V.; Balakrishnan, S.; Eapen, E.; Koshy, G.; Ambardar, N.; Vadakkepat, P.; Vaidya, D.; Lema, V.; Rijken, Y.; Tadesse, E.; Dada, O.; Sofekun, A.; Ohiaeri, C.; Runsewe-Abiodun, T.; Adewole, I.; Adeyemo, A.; Brown, B.; Oladokun, R.; Adewale, O.; Inimgba, N.; John, C.; Ogu, R.; Ekele, B.; Isah, A.; Onankpa, B.; Jamelle, R.; Junejo, D.; Ruby, Faiz N.; Gul, F.; Sherin, A.; Bangash, K.; Mahmud, G.; Masud, K.; Tasneem, N.; Gassama, S.; Soyei, A.; Agarwal, P.; Rajadurai, V.; Pirani, N.; Delport, S.; Macdonald, P.; Mokhondo, R.; Pattinson, R.; Zondo, M.; Adhikari, M.; Mnguni, N.; Moodley, J.; Carstens, M.; Kirsten, G.; Steyn, W.; Van Zyl, J.; Helwig, A.; Jacobson, S. L.; Panosche, R.; Hammond, E.; Masanganise, L. (2007)

Objective: To assess the long-term effects of in utero exposure to magnesium sulphate for children whose mothers had pre-eclampsia. Design: Assessment at 18 months of age for children whose mothers were recruited to the ...

Schizophrenia-window-of-hope.com: Development of a psycho-educational internet resource for the South African setting

Bodenstein S.; Niehaus D.J.H.; Koen L.; Wilson Z. (2010)

Psycho-educational programmes for families of persons with schizophrenia have been shown to reduce relapse rates, subsequently reducing the burden on the family as well as health care systems. Although various South African ...

Proximal renal tubular acidosis in pregnancy: A case report and literature review

Firmin C.J.; Kruger T.F.; Davids, MR (2007)

Renal tubular acidosis is usually associated with chronic renal conditions and is rarely encountered in pregnancy. It may be inherited causing osteomalacia and rickets in children or acquired following autoimmune diseases ...

Fatal hepatitis B infection despite immunization in an HIV-infected infant: A possible case of vaccine failure and immune reconstitution inflammatory syndrome

Van der Linden, D.; Cotton, M.; Rabie, H.; McKerrow, N. (2010)

We report a case of hepatitis B immune reconstitution inflammatory syndrome in an 8-month-old girl with Mycobacterium tuberculosis complex and human immunodeficiency virus (HIV) co-infection. In resource-constrained ...

Erythrocyte membrane fatty acids in patients with multiple sclerosis

Hon, G. M.; Hassan, M. S.; Van Rensburg, S. J.; Abel, S.; Marais, D. W.; Van Jaarsveld, P.; Smuts, C. M.; Henning, F.; Erasmus, R. T.; Matsha, T. (2009)

Background: Reports on fatty acids levels in multiple sclerosis remain inconclusive. Objective: To determine the erythrocyte membrane fatty acid levels in multiple sclerosis patients and correlate with Kurtzke Expanded ...

Analysis of vitamin B6 vitamers in plasma by cation-exchange high-performance liquid chromatography

Shephard G.S.; Louw M.E.J.; Labadarios D. (1987)

The aims of the present study were to evaluate the cation-exchange HPLC assay published by Coburn and Mahuren using 4'-deoxypyridoxine 5'-phosphate as an internal standard, to compare the accuracy of this method of pyridoxal ...

Selective lysis of erythrocytes infected with the trophozoite stage of Plasmodium falciparum by polyene macrolide antibiotics

Wiehart U.I.M.; Rautenbach, Marina; Hoppe H.C. (2006)

The continuous increase in strains of the human malaria parasite Plasmodium falciparum resistant to most front-line antimalarial compounds is reason for grave clinical concern. The search for new drugs led us to investigate ...

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