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Evaluation of Aspergillus niger as host for virus-like particle production, using the hepatitis B surface antigen as a model

Pluddemann A. van Zyl W.H. (2003)

The filamentous fungus Aspergillus niger was transformed with the hepatitis B virus S gene encoding the major viral envelope protein under control of the constitutive A. nidulans glyceraldehyde-3-phosphate dehydrogenase ...
Genotypic and phenotypic analysis of the Env gene from South African HIV-1 subtype B and C isolates

Treurnicht F.K. Smith T.-L. Engelbrecht S. Claassen M. Robson B.A. Zeier M. Van Rensburg E.J. (2002)

The objective of the study was to assess the genotypic and phenotypic properties of 18 viral strains from human immunodeficiency virus-1 (HIV-1) positive patients and to identify subtype C isolates for vaccine design ...
Neutralization of HIV-1 subtypes: Implications for vaccine formulations

Smith T.-L. Van Rensburg E.J. Engelbrecht S. (1998)

More than 20.8 million people are infected with HIV in sub-Saharan Africa, with South Africa having one of the fastest growing HIV-1 epidemics, where an estimated 2.4 million people were infected. Thirty-two sera from 25 ...