• Value chain-induced constraints limiting scale of conservation agriculture in South Africa 

  Von Loeper, Wolfgang Johann; Drimie, Scott; Blignaut, James (IntechOpen, 2019)

  The potential of scaling conservation agriculture (CA), for long-term food security, remains under-investigated within the context of agricultural food value chains in South Africa. To scale the use of CA an understanding ...
• Strengthening prehospital clinical practice guideline implementation in South Africa : a qualitative case study 

  McCaul, Michael; Young, Taryn; Bruijns, Stevan R.; Clarke, Mike (BMC (part of Springer Nature), 2020)

  Background: Methods on developing new (de novo) clinical practice guidelines (CPGs) have received substantial attention. However, research into alternative methods of CPG development using existing CPG documents ...
• Putting RFMix and ADMIXTURE to the test in a complex admixed population 

  Uren, Caitlin; Hoal, Eileen G.; Moller, Marlo (BMC (part of Springer Nature), 2020)

  Background: Global and local ancestry inference in admixed human populations can be performed using computational tools implementing distinct algorithms. The development and resulting accuracy of these tools has been ...
• Molecular epidemiology of drug resistant Mycobacterium tuberculosis in Africa : a systematic review 

  Chisompola, Namaunga Kasumu; Streicher, Elizabeth Maria; Muchemwa, Chishala Miriam Kapambwe; Warren, Robin Mark; Sampson, Samantha Leigh (BMC (part of Springer Nature), 2020)

  Background: The burden of drug resistant tuberculosis in Africa is largely driven by the emergence and spread of multidrug resistant (MDR) and extensively drug resistant (XDR) Mycobacterium tuberculosis strains. MDR-TB is ...
• Domestic free-range pig genetic resources in Southern Africa : progress and prospects 

  Halimani, Tinyiko Edward; Mapiye, Obvious; Marandure, Tawanda; Januarie, Diedre; Imbayarwo-Chikosi, Venancio Edward; Dzama, Kennedy (MDPI, 2020)

  Pig genetic resources in Africa originate from different regions and were introduced through several migration pathways. Genetic analysis has shown a strong phylogeographic pattern, with pigs on the eastern parts showing ...
• Constantly weighing the pig will not make it grow : do teachers teach assessment tests or the curriculum? 

  Le Cordeur, Michael (University of the Free State, 2014)

  For a number of years now, South Africa, like many other countries, has been debating a major paradigm shift in education, a shift from learning and teaching, which focused primarily on content to learning and teaching ...
• Freedom of speech and public interest, not allegiance, should underpin science advisement to government 

  Singh, Jerome Amir; Habib, Adam; Jansen, Jonathan (Health & Medical Publishing Group, 2020)

  South Africa (SA) is Africa’s science heavyweight, leading the continent in scientific output, and ranks in the top 40 globally in research productivity.[1-3] Not surprisingly, SA’s scientific and academic communities ...
• From dis-enclosure to decolonisation : in dialogue with Nancy and Mbembe on self-determination and the other 

  Gerber, Schalk Hendrik (MDPI, 2018)

  What might a sense of decolonisation (not)/be? Or, what comes after the logic of the coloniser? This question is at the centre of many debates in South Africa and extends to all countries worldwide who are faced with the ...
• The development of a single health-endorsement logo for South Africa 

  Koen, Nelene; Wentzel-Viljoen, Edelweiss; Blaauw, Renee (Cambridge University Press, 2018)

  Objective: To develop health-endorsement logos (HEL) for food products indicating healthy choices based on the South African nutrient profile model and to pilot test these logos with consumers. Design: Multistage ...
• Complete blood count reference intervals from a healthy adult urban population in Kenya 

  Omuse, Geoffrey; Maina, Daniel; Mwangi, Jane; Wambua, Caroline; Radia, Kiran; Kanyua, Alice; Kagotho, Elizabeth; Hoffman, Mariza; Ojwang, Peter; Premji, Zul; Ichihara, Kiyoshi; Erasmus, Rajiv (Public Library of Science, 2018)

  Background: There are racial, ethnic and geographical differences in complete blood count (CBC) reference intervals (RIs) and therefore it is necessary to establish RIs that are population specific. Several studies have ...
• Lamivudine monotherapy as a holding regimen for HIV-positive children 

  Patten, Gabriela; Bernheime, Jonathan; Fairlie, Lee; Rabie, Helena; Sawry, Shobna; Technau, Karl; Eley, Brian; Davies, Mary-Ann (Public Library of Science, 2018)

  Background: In resource-limited settings holding regimens, such as lamivudine monotherapy (LM), are used to manage HIV-positive children failing combination antiretroviral therapy (cART) to mitigate the risk of drug ...
• Gold exploration in two and three dimensions : improved and correlative insights from microscopy and X-Ray computed tomography 

  Chisambi, Joshua; Von der Heyden, Bjorn; Tshibalanganda, Muofhe; Le Roux, Stephan (MDPI, 2020)

  Abstract: In this contribution, we highlight a correlative approach in which three-dimensional structural/positional data are combined with two dimensional chemical and mineralogical data to understand a complex orogenic ...
• Towards 90-90 : findings after two years of the HPTN 071 (PopART) cluster-randomized trial of a universal testing-and-treatment intervention in Zambia 

  Floyd, Sian; Ayles, Helen; Schaap, Albertus; Shanaube, Kwame; MacLeod, David; Phiri, Mwelwa; Griffith, Sam; Bock, Peter; Beyers, Nulda; Fidler, Sarah; Hayes, Richard (Public Library of Science, 2018)

  Background: HPTN071(PopART) is a 3-arm community-randomised study in 21 peri-urban/urban communities in Zambia and the Western Cape of South Africa, with high HIV prevalence and high mobility especially among young adults. ...
• Gemeenskapsvertaalpraktyk : gewone taal vir die hervertaling van 'n bankteks 

  Cupido, Adriaan; Lesch, Harold (LitNet, 2020)

  Suid-Afrika is ’n land waar Engels geredelik as voorkeurtaal of oorbruggingstaal in verskeie openbare domeine gebruik word. Een van daardie domeine is die bankwese. Hierdie toedrag van sake is egter problematies, veral ...
• Limiting the spread of COVID-19 in Africa : one size mitigation strategies do not fit all countries 

  Mehtar, Shaheen; Preiser, Wolfgang; Lakhe, Ndeye Aissatou; Bousso, Abdoulaye; TamFum, Jean-Jacques Muyembe; Kallay, Oscar; Seydi, Moussa; Zumla, Alimuddin; Nachega, Jean B. (Elsevier, 2020)

  On March 11, 2020, when coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was declared a pandemic by WHO, there were comparatively few cases reported from Africa. Our ...
• Characterization and cardiovascular effects of (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone, a diterpenoid isolated from Leonotis leonurus 

  Obikeze, Kene C.; McKenzie, Jean M.; Green, Ivan R.; Mugaboa, Pierre (University of KwaZulu-Natal, 2008)

  A new diterpenoid, (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone (1), was isolated from Leonotis leonurus and the structure determined via NMR analysis. The compound causes significant changes in blood pressure of ...
• Reforming procurement law in South Africa 

  Quinot, Geo (Faculty of Law, Stellenbosch University, 2020)

  The reform of South African public procurement law has been on the cards for many years. Following years of promises from government leaders and officials about a new procurement law, a draft Public Procurement Bill for ...
• Mind the gap! Risk factors for poor continuity of care of TB patients discharged from a hospital in the Western Cape, South Africa 

  Dudley, Lilian; Mukinda, Fidele; Dyers, Robin; Marais, Frederick; Sissolak, Dagmar (Public Library of Science, 2018)

  Background: TB patients discharged from hospitals in South Africa experience poor continuity of care, failing to continue TB treatment at other levels of care. Factors contributing to poor continuity of TB care are ...
• Attrition when providing antiretroviral treatment at CD4 counts >500cells/μL at three government clinics included in the HPTN 071 (PopART) trial in South Africa 

  Bock, Peter; Fatti, Geoffrey; Ford, Nathan; Jennings, Karen; Kruger, James; Gunst, Colette; Louis, Francoise; Grobbelaar, Nelis; Shanaube, Kwame; Floyd, Sian; Grimwood, Ashraf; Hayes, Richard; Ayles, Helen; Fidler, Sarah; Beyers, Nulda (Public Library of Science, 2018-04-19)

  Introduction: WHO recommends antiretroviral treatment (ART) for all HIV-positive individuals. This study evaluated the association between baseline CD4 count and attrition in a cohort of HIV positive adults initiating ART ...
• C-Tb skin test to diagnose Mycobacterium tuberculosis infection in children and HIVinfected adults : a phase 3 trial 

  Aggerbeck, Henrik; Ruhwald, Morten; Hoff, Soren T.; Borregaard, Bettine; Hellstrom, Elizabeth; Malahleha, Mookho; Siebert, Mirna; Gani, Mashra; Seopela, Vincent; Diacon, Andreas; Lourens, Madeleine; Andersen, Peter; Dheda, Keertan (Public Library of Science, 2018)

  Background C-Tb, an ESAT-6/CFP-10-based skin test, has similar sensitivity for active TB compared to tuberculin skin test (TST) and QuantiFERON-TB-Gold-In-Tube (QFT). However, data are limited in children and HIV-infected ...

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