Prof Faadiel Essop is the current chairperson of the Depart -
ment of Physiological Sciences at Stellenbosch University. He
hails from a strong rural background; he was born in Ceres and
grew up in Paarl (Western Cape, ...
Anna-Mart Engelbrecht is currently professor in the
Department of Physiological Sciences at Stellenbosch
University. She was born in Pretoria, grew up in the Western
Cape and matriculated from DF Malan High School in ...
ENGLISH ABSTRACT: OBJECTIVES: The primary objective was to establish and compare the injury incidence in forwards
and backline players during the 2011 FNB Varsity Cup season. The secondary objective was to
establish and ...
ENGLISH ABSTRACT: While antiretroviral therapy decreases HIV/AIDS morbidity and mortality, long-term treatment results in insulin resistance and cardiovascular diseases. A possible cause of such adverse effects may be an ...
ENGLISH ABSTRACT: Background - Although acute hyperglycemic episodes are linked to lower glucose uptake, underlying mechanisms driving this process remain unclear. We hypothesized that acute hyperglycemia triggers reactive ...
ENGLISH ABSTRACT: Context: Cardiovascular diseases are the leading cause of death globally. Myocardial infarction is responsible for the highest number of deaths due to cardiovascular disease.
Objective: We have previously ...
Reyskens, Kathleen M. S. E.Fisher, Tarryn-LeeSchisler, Jonathan C.O'Connor, Wendi G.Rogers, Arlin B.Willis, Monte S.Planesse, CynthiaBoyer, FlorenceRondeau, PhilippeBourdon, EmmanuelEssop, M. F.(PLoS, 2013-11)
Although antiretroviral treatment decreases HIV-AIDS morbidity/mortality, long-term side effects may include the onset of insulin resistance and cardiovascular diseases. However, the underlying molecular mechanisms responsible ...
Reyskens, Kathleen Maria Simone Elise(Stellenbosch : Stellenbosch University, 2013-12)
ENGLISH ABSTRACT: Although antiretroviral treatment decreases HIV-AIDS morbidity/mortality, long-term effects include onset of insulin resistance and cardiovascular diseases. Increased oxidative stress and dysregulation ...
Loos, BenEngelbrecht, Anna-MartLockshin, Richard A.Klionsky, Daniel J.Zakeri, Zahra(Landes Bioscience, 2013-09)
Impaired autophagic machinery is implicated in a number of diseases such as heart disease, neurodegeneration and cancer. A common denominator in these pathologies is a dysregulation of autophagy that has been linked to a ...
Wlodzimirow, K. A.Eslami, S.Chamuleau, R. A. F. M.Nieuwoudt, M.Abu-Hanna, A.(PLOS, 2012-12-14)
Introduction: Acute liver failure is a rare disease with high mortality and liver transplantation is the only life saving therapy.
Accurate prognosis of ALF is crucial for proper intervention.
Aim: To identify and ...
ENGLISH ABSTRACT: Contusion injuries cause significant muscle damage, activating a series of cellular events. Satellite cells (SC), the key role players in muscle regeneration, are activated to proliferate and develop into ...
ENGLISH ABSTRACT: Introduction
Cisplatin has been widely used to treat solid tumours and much success has come from the use of this drug in the treatment of head and neck, ovarian, testicular, cervical and small-cell lung ...
ENGLISH ABSTRACT: Introduction:
Among the cancers that afflict females world-wide, neoplastic disease of breast tissue is the most frequently diagnosed form and the leading cause of cancer-related death. Conventional ...
ENGLISH ABSTRACT: Introduction: Breast cancer is a major contributor to mortality in women worldwide. Although, anthracyclines, such as doxorubicin, are among the most valuable treatments for breast cancer, their clinical ...
ENGLISH ABSTRACT: Introduction
Diabetes constitutes a major health challenge. Since cardiovascular complications are common in
diabetic patients this will further increase the overall burden of disease. Furthermore, ...
Van de Vyver, Mari(Stellenbosch : Stellenbosch University, 2013-03)
ENGLISH ABSTRACT: Background: Understanding the contribution of divergent individual response patterns remains a key objective in identifying mechanisms of inflammation and potential factors limiting the resolution of ...
Le Roux, Heloise(Stellenbosch : Stellenbosch University, 2012-12)
ENGLISH ABSTRACT: Introduction: Cancer is an emerging health problem in South Africa, with breast cancer being one of the leading cancers affecting women globally. Therefore, there is a need to find novel targets to improve ...
ENGLISH ABSTRACT: Context: There are serious deficiencies in the current tests and criteria available for the diagnosis of diabetes. A novel screening method for the earlier and more efficient detection of type 2 diabetes ...
Background: While Selection of reverse transcriptase (RT) mutation has been
reported frequently, protease (PR) mutations on antiretroviral therapy (ART) including
boosted Protease inhibitor (PI) have not been reported ...