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Highly efficient L-lactate production using engineered Escherichia coli with dissimilar temperature optima for L-lactate formation and cell growth

Niu, Dandan; Tian, Kangming; Prior, Bernard A.; Wang, Min; Wang, Zhengxiang; Lu, Fuping; Singh, Suren (BioMed Central, 2014)

L-Lactic acid, one of the most important chiral molecules and organic acids, is produced via pyruvate from carbohydrates in diverse microorganisms catalyzed by an NAD+-dependent L-lactate dehydrogenase. Naturally, Escherichia ...
Improved ethanol productivity from lignocellulosic hydrolysates by Escherichia coli with regulated glucose utilization

Sun, Jinfeng; Tian, Kangming; Wang, Jie; Dong, Zixing; Liu, Xiaoguang; Permaul, Kugenthiren; Singh, Suren; Prior, Bernard A.; Wang, Zhengxiang (BioMed Central, 2018-05-02)

Background: Lignocellulosic ethanol could offer a sustainable source to meet the increasing worldwide demand for fuel. However, efficient and simultaneous metabolism of all types of sugars in lignocellulosic hydrolysates ...