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Tuberculosis contact investigation in a high-burden setting: House or household?

dc.contributor.authorVan Wyk S.S.
dc.contributor.authorMandalakas A.M.
dc.contributor.authorEnarson D.A.
dc.contributor.authorGie R.P.
dc.contributor.authorBeyers N.
dc.contributor.authorHesseling A.C.
dc.date.accessioned2012-02-15T08:18:35Z
dc.date.available2012-02-15T08:18:35Z
dc.date.issued2012
dc.identifier.citationInternational Journal of Tuberculosis and Lung Disease
dc.identifier.citation16
dc.identifier.citation2
dc.identifier.citation157
dc.identifier.citation162
dc.identifier.issn10273719
dc.identifier.other10.5588/ijtld.11.0393
dc.identifier.urihttp://hdl.handle.net/10019.1/19755
dc.description.abstractSETTING: A high tuberculosis (TB) burden setting, South Africa. Two frequently used definitions for 'household' are 1) 'all dwellings on the same plot of land that share the same residential address'; and 2) 'a group of persons who live together in the same dwelling unit and who have the same eating arrangements'. OBJECTIVE: To characterise a household and the outcome of investigations in household child contacts using definition 1 compared to definition 2 during a TB contact investigation. DESIGN: Access to a household (definition 1) was gained via an adult TB case. Children were assessed for TB infection and disease. RESULTS: Household enumeration indicated 25 members of three families living in a main house and a fourth family living in an adjacent structure. Three children were diagnosed with TB and two referred for isoniazid preventive therapy. Families living in the main house shared the main kitchen, while the yard house family used its own kitchen. This household would have been classified as two separate households if definition 2 had been used, and children with TB disease and infection would have been missed. CONCLUSION: The definition of household in TB contact investigation should provide a framework that is broad enough to capture the majority of children at risk. © 2012 The Union.
dc.subjectisoniazid
dc.subjectadolescent
dc.subjectadult
dc.subjectarticle
dc.subjectbacterial transmission
dc.subjectbacterium culture
dc.subjectchild
dc.subjectcontact examination
dc.subjectcontrolled study
dc.subjecthousehold
dc.subjecthuman
dc.subjectinfection risk
dc.subjectinterferon gamma release assay
dc.subjectMycobacterium tuberculosis
dc.subjectpreschool child
dc.subjectpriority journal
dc.subjectschool child
dc.subjectthorax radiography
dc.subjecttuberculin test
dc.subjecttuberculosis
dc.titleTuberculosis contact investigation in a high-burden setting: House or household?
dc.typeArticle


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