Now showing items 1-3 of 3
Enabling multiscale modeling in systems medicine
(BioMed Central, 2014-03)
[See article for abstract].
Parameter identifiability and sensitivity analysis predict targets for enhancement of STAT1 activity in pancreatic cancer and stellate cells
(Public Library of Science, 2012-12)
The present work exemplifies how parameter identifiability analysis can be used to gain insights into differences in experimental systems and how uncertainty in parameter estimates can be handled. The case study, presented ...
Anti-inflammatory effects of reactive oxygen species : a multi-valued logical model validated by formal concept analysis
(BioMed Central, 2014-09)
Background: Recent findings suggest that in pancreatic acinar cells stimulated with bile acid, a pro-apoptotic effect of reactive oxygen species (ROS) dominates their effect on necrosis and spreading of inflammation. The ...