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  • Pharmacokinetics of recombinant activated factor VII in trauma patients with severe bleeding 

    Klitgaard, Thomas; Tabanera y Palacios, Rene; Boffard, Kenneth; Lau, Philip T. C.; Warren, Brian; Rizoli, Sandro; Rossaint, Rolf; Kluger, Yoram; Riou, Bruno (BioMed Central, 2006-07)
    Introduction: Recombinant activated factor VII (rFVIIa) has been used as adjunctive therapy in trauma patients with severe bleeding. However, its pharmacokinetics profile remains unknown. Methods: In two placebo-controlled ...