Background: Population-based data on the burden of chronic kidney disease (CKD) in sub-Saharan Africa
is still very limited. We assessed the prevalence and determinants of CKD, and evaluated the
concordance of commonly ...
ENGLISH ABSTRACT: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease in the world. The disease spectrum of NAFLD extends from steatosis (types 1,2) to non-alcoholic steatohepatitis (NASH) ...
ENGLISH ABSTRACT: The purpose of this study was to investigate the association of the selected MYH9 single nucleotide polymorphisms (SNPs) with chronic kidney disease (CKD) and its related co-morbidities in the South African ...
ENGLISH ABSTRACT: Background/Aims: Obesity has increased rapidly in South African children and adolescents with
significant variability observed among racial groups. Genes that regulate appetite have been studied in
different ...
Background: HbA1c has been the gold standard for glycaemic control follow-up for decades. In 2009, a level of 6.5%
(48 mmol/mol) was proposed as diagnostic for diabetes. We test this cut-off in our community.
Methods: ...
Janse Van Rensburg, SusanKotze, Maritha J.Van Toorn, Ronald(Springer US, 2012-03)
Although the involvement of immune mechanisms
in multiple sclerosis (MS) is undisputed, some argue
that there is insufficient evidence to support the hypothesis
that MS is an autoimmune disease, and that the difference
between ...
ENGLISH ABSTRACT: Background: Serum free light chains (FLC) are associated with imbalances in heavy and light
chain production. Abnormal FLC ratios have been associated with risk of progression in certain
diseases. ...
Le Riche, Mia(Stellenbosch : Stellenbosch University, 2007-12)
ENGLISH ABSTRACT: Lipoprotein X (LpX) is an abnormal cholesterol-containing particle that may be present in the serum of subjects with cholestasis, lecithin:cholesterol acyltransferase (LCAT) deficiency and parenteral ...
Malan ChristinaDonald, P. R.Odendaal , H. J.Shanley , B. C.(HMPG, 1978-08)
The relationship between the concentration of alphal-fetoprotein
(AFP) in cord blood and neonatal jaundice has
been examined in 259 neonates. Cord blood AFP varies
inversely with gestational age, as does the incidence ...
Zemlin, Annalise E.Nutt, LouiseBurgess, Lesley J.Eiman, FredelineErasmus, Rajiv T.(Health and Medical Publishing Group (HMPG), 2009)
Background. Various publications have highlighted the significance of laboratory errors in the pre- and post-analytical phases and their impact on results. Thyroid-stimulating hormone (TSH) is a first-line thyroid function ...
De Klerk, M.Weideman, A.Malan, C.Shanley, B. C.(Health and Medical Publishing Group (HMPG), 1975)
The relationship between urinary excretion of porphyrins, porphyrin precursors and total oestrogens in normal pregnancy was investigated. Significant increases in total oestrogen, delta aminolaevulinic acid (ALA) and ...
Shanley, B. C.Neethling, A. C.Percy, V. A.Carstens, M.(Health and Medical Publishing Group (HMPG), 1975)
It has been proposed that delta aminolaevulinic acid (ALA), which is overproduced in the inherited hepatic porphyrias, may be responsible for the neurological manifestations of the acute attacks seen in these disorders. ...
Le Riche, MiaZemlin, Annalise E.Erasmus, Rajiv T.Davids, M. Razeen(Health and Medical Publishing Group (HMPG), 2007-10)
BACKGROUND: Internationally, clinical guidelines recommend the use of creatinine-based equations to estimate glomerular filtration rate (GFR) for assessment and follow-up of kidney disease. The routine use of 24-hour ...
Jalali Sefid Dashti, Mahjoubeh(Stellenbosch : University of Stellenbosch, 2010-12)
ENGLISH ABSTRACT: The aetiology of multiple sclerosis (MS) remains largely unknown, due to its multifactorial nature with environmental and genetic factors contributing to the risk. Several investigations highlighted the ...