• The necessity for T-cryptantigen activation screening in babies with necrotising enterocolitis 

      Kirsten, G. F.; Smith, J.; Pieper, C.; Bird, A.; Wessels, G.; Riphagen, S.; Moore, S. (Health & Medical Publishing Group, 1996)
      Objective. To determine the prevalence of T-cryptantigen activation (TCA) and its predictive value for severity of necrotising enterocolitis (NEC) in babies. Study design. Prospective descriptive. Study population. Thirty-four ...
    • Necrotising enterocolitis as an infectious disease : evidence from an outbreak of invasive disease due to extended-spectrum beta-lactamase-producing Klebsiella pneumoniae [2] 

      Cotton, M. F.; Pieper, C. H.; Kirsten, G. F.; Orth, H.; Theron, D. C. (Health & Medical Publishing Group, 2001)
      Necrotising enterocolitis (NEC) is a severe gastro-intestinal disorder, predominantly seen in hospitalised low-birth-weight newborn infants. It is associated with significant morbidity and mortality. Infants with NEC ...
    • The need to repeat lumbar puncture 

      Soskolne, E. I.; Kuhn, S. H.; Van Der Merwe P. L.; Keet, M. P. (Health & Medical Publishing Group, 1977)
      4 Patients with bacterial meningitis are reported. On initial examination, 1 patient had a slightly abnormal cerebrospinal fluid (CSF), and in the other 3 patients, the CSF was completely normal. An obviously purulent CSF ...
    • Neonatal and paediatric bloodstream infections : pathogens, antimicrobial resistance patterns and prescribing practice at Khayelitsha District Hospital, Cape Town, South Africa 

      Crichton, H.; O'Connell, N.; Rabie, H.; Whitelaw, A. C.; Dramowski, Angela (Health & Medical Publishing Group, 2018)
      Background. The epidemiology of neonatal and paediatric community-acquired and healthcare-associated bloodstream infections (BSI) at South African (SA) district hospitals is under-researched. Objective. Retrospective ...
    • Neonatal listeriosis during a countrywide epidemic in South Africa : a tertiary hospital’s experience 

      Dramowski, Angela; Lloyd, L. G.; Bekker, A.; Holgate, S.; Aucamp, M.; Reddy, K.; Finlayson, H. (Health & Medical Publishing Group, 2018)
      Background. A countrywide epidemic of Listeria monocytogenes (LM) in South Africa began in the first quarter of 2017, rapidly becoming the world’s largest LM outbreak to date. Methods. We describe the clinical course ...
    • Nephroblastoma - a 25 year review of a South African unit 

      Visser, Yolandi Thelma; Uys, Ronelle; Van Zyl, Anel; Stefan, Daniela Cristina (PubMed Central, 2014-09-15)
      Rationale: To determine the outcome of patients with nephroblastoma in a South African hospital. Objective: To determine if there is a difference in the outcome of patients with nephroblastoma comparing two treatment ...
    • Nephrotic syndrome in Namibian children 

      Van Buuren, A. J.; Bates, W. D.; Muller, N. (Health & Medical Publishing Group, 1999)
      Background and objectives. Patterns of nephrotic syndrome vary between regions and countries, and influence approaches to management. In the mid-1970s the University of Stellenbosch became involved in providing tertiary ...
    • Neurodevelopment at 11 months after starting antiretroviral therapy within 3 weeks of life 

      Laughton, Barbara; Naidoo, Shalena; Dobbels, Els; Boivin, Michael J.; Janse van Rensburg, Anita; Glashoff, Richard H.; Van Zyl, Gert U.; Kruger, Mariana; Cotton, Mark F. (AOSIS, 2019-10-03)
      Background: Antiretroviral therapy (ART) started between 7 and 12 weeks of age improves neurodevelopmental outcomes in HIV-infected (HIV+) infants, but the impact of even earlier initiation is not yet described. Objectives: ...
    • Neurodevelopment in perinatally HIV-infected children : a concern for adolescence 

      Laughton, Barbara; Cornell, Morna; Boivin, Michael; Van Rie, Annelies (International AIDS Society, 2013-06-18)
      Globally, an estimated 3.4 million children are living with HIV, yet little is known about the effects of HIV and antiretroviral treatment (ART) on the developing brain, and the neurodevelopmental and behavioural outcomes ...
    • Neurodevelopmental and behavioural outcome of the HIV-exposed uninfected infant and child 

      Springer, Priscilla Estelle (Stellenbosch : Stellenbosch University., 2020-03)
      ENGLISH ABSTRACT: The first 1000 days of life represents a crucial phase for cognitive, language and emotional development. Indeed, early childhood development provides a foundation for educational and vocational success. ...
    • Neurodevelopmental status of HIV-exposed but uninfected children : a pilot study 

      Springer, P.; Laughton, Barbara; Tomlinson, M.; Harvey, J.; Esser, M. (Health & Medical Publishing Group, 2012-03-29)
      Introduction. HIV affects children both directly and indirectly, with evidence of increased infectious mortality and morbidity in the HIV-exposed but uninfected (HEU) infant. There is little published research on ...
    • Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children 

      Violari, Avy; Paed, F. C.; Lindsey, Jane C.; Hughes, Michael D.; Mujuru, Hilda A.; Barlow-Mosha, Linda; Kamthunzi, Portia; Chi, Benjamin H.; Cotton, Mark F.; Moultrie, Harry; Khadse, Sandhya; Schimana, Werner; Bobat, Raziya; Purdue, Lynette; Eshleman, Susan H.; Abrams, Elaine J.; Millar, Linda; Petzold, Elizabeth; Mofenson, Lynne M.; Jean-Philippe, Patrick; Palumbo, Paul (Massachusetts Medical Society, 2012)
      BACKGROUND: Nevirapine-based antiretroviral therapy is the predominant (and often the only) regimen available for children in resource-limited settings. Nevirapine resistance after exposure to the drug for prevention of ...
    • New resuscitation connexion 

      Thom J.C. (HMPG, 1974-03)
      [No abstract available]
    • No evidence of HIV replication in children on antiretroviral therapy 

      Van Zyl, Gert U.; Katusiime, Mary Grace; Wiegand, Ann; McManus, William R.; Bale, Michael J.; Halvas, Elias K.; Luke, Brian; Boltz, Valerie F.; Spindler, Jonathan; Laughton, Barbara; Engelbrecht, Susan; Coffin, John M.; Cotton, Mark F.; Shao, Wei; Mellors, John W.; Kearney, Mary F. (American Society for Clinical Investigation, 2017-04)
      ENGLISH ABSTRACT: It remains controversial whether current antiretroviral therapy (ART) fully suppresses the cycles of HIV replication and viral evolution in vivo. If replication persists in sanctuary sites such as the ...
    • Nosocomial endocarditis due to extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a child 

      Shipton, S. E.; Cotton, M. F.; Wessels, G.; Wasserman, E. (Health & Medical Publishing Group, 2001)
      Extended-spectrum beta-lactamase-producing organisms resistant to third-generation cephalosporins have been increasingly implicated in nosocomial infection.'Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae ...
    • Novel application of NIH case definitions in a paediatric tuberculosis contact investigation study 

      Wiseman, C. A.; Mandalakas, A. M.; Kirchner, H. L.; Gie, R. P.; Schaaf, H. Simon; Walters, E.; Hesseling, A. C. (International Union Against Tuberculosis and Lung Disease, 2015-04)
      BACKGROUND: International (National Institutes of Health [NIH]) case definitions have been proposed for paediatric tuberculosis (TB) diagnostic studies. The relevance of these definitions for contact tracing studies is ...
    • Nutritional support of children with chronic liver disease 

      Nel, Etienne D.; Terblanche, A. J. (Health & Medical Publishing Group, 2015)
      Anorexia, malabsorption and metabolic derangements contribute to the malnutrition that occurs in most children with chronic liver disease. Nutritional support should be started early in the management of these children ...
    • Observed full blood count and lymphocyte subset values in a cohort of clinically healthy South African children from a semi-informal settlement in Cape Town 

      Lawrie, Denise; Payne, Helen; Nieuwoudt, Martin; Glencross, Deborah Kim (Health & Medical Publishing Group, 2015-09)
      Background. The paediatric full blood count and lymphocyte subset reference intervals used by the National Health Laboratory Service (NHLS), South Africa (SA), are taken from two international reference interval publications. ...
    • Obstructive jaundice and hydatid cysts mimicking choledochal cyst 

      Saczek, K.; Moore, S. W.; De Villiers, R.; Blaszczyk, M. (Health and Medical Publishing Group (HMPG), 2007-09)
      Hydatid disease remains a common problem in endemic regions throughout the world. Endemic areas include Australasia, Africa, the Americas, the Middle East, Greece, Spain and Eastern Europe. Hydatid cysts (HCs) typically ...
    • Obstructive pulmonary disease in patients with previous tuberculosis : pathophysiology of a community-based cohort 

      Allwood, Brian W.; Gillespie, Rencia; Galperin-Aizenberg, Maya; Bateman, Mary; Olckers, Helena; Taborda-Barata, Luis; Calligaro, Gregory L.; Said-Hartley, Qonita; Van Zyl-Smit, Richard; Cooper, Christopher B.; Van Rikxoort, Eva; Goldin, Jonathan; Beyers, Nulda; Bateman, Eric D. (Health & Medical Publishing Group, 2017)
      Background. An association between chronic airflow limitation (CAL) and a history of pulmonary tuberculosis (PTB) has been confirmed in epidemiological studies, but the mechanisms responsible for this association are ...