Now showing items 1-2 of 2
An investigation into the influence of rooibos (Aspalathus linearis) on androgen metabolism in normal and prostate cancer cells
(Stellenbosch : Stellenbosch University, 2015-04)
ENGLISH ABSTRACT: In this study, the influence of rooibos on the catalytic activity of enzymes 17β -hydroxysteroid dehydrogenase type 3 (17βHSD3), 17β-hydroxysteroid dehydrogenase type 5 (AKR1C3), 17β-hydroxysteroid ...
The metabolism of 11β-hydroxyandrostenedione by steroidogenic enzymes yields metabolites contributing to the androgen pool in prostate cancer
(Stellenbosch : Stellenbosch University, 2018-03)
ENGLISH ABSTRACT: This study describes: • The development and validation of three ultra-performance convergence chromatography tandem mass spectrometry (UPC2-MS/MS) analytical methods which were applied in the detection ...