Now showing items 1-2 of 2
Circadian rhythms as novel chemotherapeutic strategies for breast cancer
(Stellenbosch : Stellenbosch University, 2014-12)
ENGLISH ABSTRACT: Introduction: Mammalian circadian rhythms form an integral physiological system allowing for the synchronisation of all metabolic processes to daily light/dark cycles, thereby optimising their efficacy. ...
Metabolic reprograming and cancer resistance : an investigation into the metabolic control of cancer-associated fibroblasts on breast cancer cell survival and metastasis
(Stellenbosch : Stellenbosch University, 2018-03)
ENGLISH ABSTRACT: Introduction: Cancer-associated fibroblasts (CAFs) constitute the most abundant mesenchymal cell type present within the tumour microenvironment. Recent evidence suggests that nutrient deprived cancer ...