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Partial inhibition of the ubiquitin– proteasome system ameliorates cardiac dysfunction following ischemia–reperfusion in the presence of high glucose
(Springer Verlag, 2015)
Abstract Background: Acute hyperglycemia co-presenting with myocardial infarction (in diabetic and non-diabetic individuals) is often associated with a poor prognosis. Although acute hyperglycemia induces oxidative stress ...
Oxidatives stress and adipocyte biology : focus on therole of AGEs
Diabetes is a major health problem that is usually associated with obesity, together with hyperglycemia and increased advanced glycation endproducts (AGEs) formation. Elevated AGEs elicit severe downstream consequences ...
Aspalathin protects the heart against hyperglycemia-induced oxidative damage by up-regulating Nrf2 expression
Aspalathin (ASP) can protect H9c2 cardiomyocytes against high glucose (HG)-induced shifts in myocardial substrate preference, oxidative stress, and apoptosis. The protective mechanism of ASP remains unknown. However, as ...