Now showing items 1-4 of 4
Unravelling the interconnections of cellular regulation
(Stellenbosch : Stellenbosch University, 2012-10)
Johann Rohwer was born in Greytown on 25 May 1968 and grew up in the German settlement Hermannsburg in the KwaZulu-Natal Midlands. He received all his schooling at the Deutsche Schule Hermannsburg. After matriculating ...
The logic of kinetic regulation in the thioredoxin system
(BioMed Central, 2011-01)
Abstract: Background: The thioredoxin system consisting of NADP(H), thioredoxin reductase and thioredoxin provides reducing equivalents to a large and diverse array of cellular processes. Despite a great deal of information ...
Impact of glucocorticoid receptor density on ligand- independent dimerization, cooperative ligand-binding and basal priming of transactivation : a cell culture model
(Public Library of Science -- PLoS, 2013-05)
Glucocorticoid receptor (GR) levels vary between tissues and individuals and are altered by physiological and pharmacological effectors. However, the effects and implications of differences in GR concentration have not ...
The glutaredoxin mono- and di-thiol mechanisms for deglutathionylation are functionally equivalent : implications for redox systems biology
(Portland Press, 2015)
Glutathionylation plays a central role in cellular redox regulation and anti-oxidative defence. Grx (Glutaredoxins) are primarily responsible for reversing glutathionylation and their activity therefore affects a range ...