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Gender differences in metabolic risk factor prevalence in a South African student population

Smith, Carine; Essop, M. Faadiel (Clinics Cardiv Publishing, 2009-06)

We determined selected risk factors for the metabolic syndrome and assessed the metabolic risk status (using IDF criteria) of third-year physiology students at Stellenbosch University (88 males and 178 females). Outcome ...

Distinct gender differences in anthropometric profiles of a peri-urban South African HIV population : a cross sectional study

Nell, Theodore A.; Kruger, Maritza J.; Beukes, Dillan C.; Calitz, Esme; Essop, Rehana; Essop, M. Faadiel (BioMed Central, 2015-02)

Background: Highly active antiretroviral therapy (HAART) has extended life expectancy and enhanced the well-being of HIV-positive individuals. Since there are concerns regarding HAART-mediated onset of cardio-metabolic ...

Partial inhibition of the ubiquitin– proteasome system ameliorates cardiac dysfunction following ischemia–reperfusion in the presence of high glucose

Adams, Buin; Mapanga, Rudo F.; Essop, M. Faadiel (Springer Verlag, 2015)

Abstract Background: Acute hyperglycemia co-presenting with myocardial infarction (in diabetic and non-diabetic individuals) is often associated with a poor prognosis. Although acute hyperglycemia induces oxidative stress ...

Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet

Quintana, Megan T.; He, Jun; Sullivan, Jenyth; Grevengoed, Trisha; Schisler, Jonathan; Han, Yipin; Hill, Joseph A.; Yates, Cecelia C.; Stansfield, William E.; Mapanga, Rudo F.; Essop, M. Faadiel; Muehlbauer, Michael J.; Newgard, Christopher B.; Bain, James R.; Willis, Monte S. (BioMed Central, 2015-07)

Background: The pathogenesis of diabetic cardiomyopathy (DCM) involves the enhanced activation of peroxisome proliferator activating receptor (PPAR) transcription factors, including the most prominent isoform in the ...

Oxidatives stress and adipocyte biology : focus on therole of AGEs

Boyer, Florence; Vidot, Jennifer Baraka; Dubourg, Alexis Guerin; Rondeau, Philippe; Essop, M. Faadiel; Bourdon, Emmanuel (Hindawi, 2015-03)

Diabetes is a major health problem that is usually associated with obesity, together with hyperglycemia and increased advanced glycation endproducts (AGEs) formation. Elevated AGEs elicit severe downstream consequences ...

Resveratrol co-treatment attenuates the effects of HIV protease inhibitors on rat body weight and enhances cardiac mitochondrial respiration

Symington, Burger; Mapanga, Rudo F.; Norton, Gavin R.; Essop, M. Faadiel (Public Library of Science, 2017-01-20)

Since the early 1990s human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) emerged as a global health pandemic, with sub-Saharan Africa the hardest hit. While the successful roll-out of antiretroviral ...