Now showing items 1-2 of 2

    • Abrogation of glucocorticoid receptor dimerization correlates with dissociated glucocorticoid behavior of compound A 

      Robertson, Steven; Allie-Reid, Fatima; Vanden Berghe, Wim; Visser, Koch; Binder, Anke; Africander, Donita; Vismer, Michael; De Bosscher, Karolien; Hapgood, Janet; Haegeman, Guy; Louw, Ann (HighWire Press, 2010-03)
      Compound A (CpdA), a dissociated glucocorticoid receptor modulator, decreases corticosteroid-binding globulin (CBG), adrenocorticotropic hormone (ACTH), and luteneinizing hormone levels in rats. Whether this is due to ...

    • Not all progestins are the same : implications for usage 

      Hapgood, Janet P.; Koubovec, Dominique; Louw, Ann; Africander, Donita (Elsevier, 2004-11)
      Recent clinical evidence showing unexpected side-effects of progestins used in contraception and hormone replacement therapy has highlighted the importance of choice of synthetic progestin. The molecularmechanisms of ...