Dihydrotestosterone (DHT) is regarded as the most potent natural androgen and is implicated in the development and progression of castration resistant prostate cancer (CRPC). Under castrate conditions, DHT is produced from ...

Video footage of M11 and M12 team members during take over. Left to right: W. Thiele (M11, Mechanic), C.J Grobler (M11, Meteorologist) and Barry Jackson (M12, Mechanic).

The biological significance of 11β-hydroxyandrostenedione (11OHA4) has eluded researchers for the past six decades. It is now known that 11OHA4 is biosynthesized in the androgen arm of the adrenal steroidogenesis pathway ...

ENGLISH ABSTRACT: Physiological and behavioural responses to changes in temperature may enable ectotherms to buffer the effects of climate change or facilitate movement into novel environments. The thermal biology of the ...

Photographic slideshow of the 27th Gough Expedition.

Dudley Rowswell's film of his year on Marion Island as a member of the 33rd expedition.

ENGLISH ABSTRACT: The United Nations Convention on the Law of the Sea (UNCLOS) provides an opportunity for qualifying coastal signatory states to claim extended maritime estate. The opportunity to claim rests on the ...

ENGLISH ABSTRACT: Extracting data from video streams and using the data to better understand the observed world allows many systems to automatically perform tasks that ordinarily needed to be completed by humans. One ...

ENGLISH ABSTRACT: The aim of this thesis is to develop a generic 3D virtual environment development platform for autism spectrum disorder (ASD) therapy tools. The potential of using computerised therapy tools for ASD ...

New species of Emmonsia-like fungi, with phylogenetic and clinical similarities to Blastomyces and Histoplasma, have emerged as causes of systemic human mycoses worldwide. They differ from classical Emmonsia species by ...

The identification of selective glucocorticoid receptor (GR) modifiers, which separate transactivation and transrepression properties, represents an important research goal for steroid pharmacology. Although the gene-activating ...

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The Reversible addition fragmentation chain transfer (RAFT) technique is a robust and versatile technique that enables the synthesis of polymers of controlled molecular weight and polydispersity. The application of the ...

ENGLISH ABSTRACT: A thorough search through the literature as well as through the Cambridge Crystallographic Structural Database resulted in no examples of a neutral ozone acting as ligand in a complex with any metal. ...

ENGLISH ABSTRACT: Antibiotic resistance has become a major threat to humankind, necessitating research and development of alternative antimicrobial compounds. Many bacteria, including lactic acid bacteria, produce small ...

Metals are natural elements of the earth crust usually present at low concentrations in all soils. Although many metals such as cobalt, copper, iron and zinc are essential to living organisms, at elevated concentrations ...

Compound A (CpdA), a dissociated glucocorticoid receptor modulator, decreases corticosteroid-binding globulin (CBG), adrenocorticotropic hormone (ACTH), and luteneinizing hormone levels in rats. Whether this is due to ...

ENGLISH ABSTRACT: The agricultural sector in South Africa relies heavily on the use of pesticides to protect crops against pest organisms. Pesticides can affect non-target organisms such as the meso- and macrofauna in ...

Film footage of the accident at sea in which Petty Officer Bold lost his life. The men were transporting goods to be offloaded on the Marion Island coast and the boats capsized.

ENGLISH ABSTRACT: Evidence for widespread ecological impacts due to rapid climate change is on the increase, with further warming predicted over the next century. This increase in warming has lead to organisms adjusting ...