The Faculty of Science is respected within South Africa, Africa and the world arena as a knowledge-partner of note that builds on the scientific, technological and intellectual capacity of Africa and plays an active role in the development of South African society. The faculty is placed in the top 300 within the category Natural Sciences of the QS World University Ranking list.

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Recent Submissions

  • Modelling the role of correctional services on gangs : insights through a mathematical model 

    Nyabadza, F.; Ogbogbo, C. P.; Mushanyu, J. (Royal Society, 2017)
    Research has shown that gang membership increases the chances of offending, antisocial behaviour and drug use. Gang membership should be acknowledged as part of crime prevention and policy designs, and when developing ...
  • Host-seeking efficiency can explain population dynamics of the tsetse fly Glossina morsitans morsitans in response to host density decline 

    Lord, Jennifer S.; Mthombothi, Zinhle; Lagat, Vitalis K.; Atuhaire, Fatumah; Hargrove, John W. (Public Library of Science, 2017)
    Females of all blood-feeding arthropod vectors must find and feed on a host in order to produce offspring. For tsetse—vectors of the trypanosomes that cause human and animal African trypanosomiasis—the problem is more ...
  • Superfluid filaments of dipolar bosons in free space 

    Cinti, Fabio; Cappellaro, Alberto; Salasnich, Luca; Macri, Tommaso (American Physical Society, 2017)
    We systematically investigate the zero temperature phase diagram of bosons interacting via dipolar interactions in three dimensions in free space via path integral Monte Carlo simulations with a few hundreds of particles ...
  • Examination of evidence for collinear cluster tri-partition 

    Pyatkov, Yu. V.; Kamanin, D. V.; Alexandrov, A. A.; Alexandrova, I. A.; Goryainova, Z. I.; Malaza, V.; Mkaza, N.; Kuznetsova, E. A.; Strekalovsky, A. O.; Strekalovsky, O. V.; Zhuchko, V. E. (American Physical Society, 2017)
    Background: In a series of experiments at different time-of-flight spectrometers of heavy ions we have observed manifestations of a new at least ternary decay channel of low excited heavy nuclei. Due to specific features ...
  • Are invasive populations characterized by a broader diet than native populations? 

    Courant, Julien; Vogt, Solveig; Marques, Raquel; Measey, John; Secondi, Jean; Rebelo, Rui; De Villiers, Andre; Ihlow, Flora; De Busschere, Charlotte; Backeljau, Thierry; Rodder, Dennis; Herrel, Anthony (PeerJ, 2017)
    Background. Invasive species are among the most significant threats to biodiversity. The diet of invasive animal populations is a crucial factor that must be considered in the context of biological invasions. A broad ...
  • Targeted NGS for species level phylogenomics : "made to measure'' or "one size fits all''? 

    Kadlec, Malvina; Bellstedt, Dirk U.; Le Maitre, Nicholas C.; Pirie, Michael D. (PeerJ, 2017)
    Targeted high-throughput sequencing using hybrid-enrichment offers a promising source of data for inferring multiple, meaningfully resolved, independent gene trees suitable to address challenging phylogenetic problems ...
  • FAIRDOMHub : a repository and collaboration environment for sharing systems biology research 

    Wolstencroft, Katherine; Krebs, Olga; Snoep, Jacky L.; Stanford, Natalie J.; Bacall, Finn; Golebiewski, Martin; Kuzyakiv, Rostyk; Nguyen, Quyen; Owen, Stuart; Soiland-Reyes, Stian; Straszewski, Jakub; Van Niekerk, David D.; Williams, Alan R.; Malmstrom, Lars; Rinn, Bernd; Muller, Wolfgang; Goble, Carole (Oxford University Press on behalf of Nucleic Acids Research, 2017)
    The FAIRDOMHub is a repository for publishing FAIR (Findable, Accessible, Interoperable and Reusable) Data, Operating procedures and Models ( for the Systems Biology community. It is a web-accessible ...
  • No saturation in the accumulation of alien species worldwide 

    Seebens, Hanno; Blackburn, T. M.; Dyer, E. E.; Genovesi, P.; Hulme, P. E.; Jeschke, J. M.; Pagad, S.; Pysek, P.; Winter, M.; Arianoutsou, M.; Bacher, S.; Blasius, B.; Brundu, G.; Capinha, G.; Celesti-Grapow, L.; Dawson, W.; Dullinger, S.; Fuentes, N.; Jager, H.; Kartesz, J.; Kenis, M.; Kreft, H.; Kuhn, I; Lenzner, B.; Liebhold, A.; Mosena, A.; Moser, D.; Nishino, M.; Pearman, D.; Pergl, J.; Rabitsch, W.; Rojas-Sandoval, J.; Roques, A.; Rorke, S.; Rossinelli, S.; Roy, H. E.; Scalera, R.; Schindler, S.; Stajerova, K.; Tokarska-Guzik, B.; Van Kleunen, M.; Walker, K.; Weigelt, P.; Yamanaka, T.; Essl, F. (Nature Research (part of Springer Nature), 2017)
    Although research on human-mediated exchanges of species has substantially intensified during the last centuries, we know surprisingly little about temporal dynamics of alien species accumulations across regions and taxa. ...
  • Raising the flag on marine alien fouling species 

    Peters, Koebraa; Sink, Kerry; Robinson, Tamara B. (Regional Euro-Asian Biological Invasions Centre, 2017)
    Harbours are known introduction foci of marine alien species. They act as recipients of new introductions and as sources for regional spread. We report on subtidal surveys of fouling communities from 14 harbours along the ...
  • Status and trends in the global growth of Koedoe between 1958 and 2016 

    Foxcroft, Llewellyn C.; Herbst, Marna (AOSIS Publishing, 2017)
    No abstract available.
  • A preliminary assessment of the extent and potential impacts of alien plant invasions in the Serengeti-Mara ecosystem, East Africa 

    Witt, Arne B. R.; Kiambi, Sospeter; Beale, Tim; Van Wilgen, Brian W. (AOSIS Publishing, 2017)
    This article provides a preliminary list of alien plant species in the Serengeti-Mara ecosystem in East Africa. The list is based on broad-scale roadside surveys in the area and is supplemented by more detailed surveys ...
  • Central intracrine DHEA synthesis in ageing-related neuroinflammation and neurodegeneration : therapeutic potential? 

    Powrie, Y. S. L.; Smith, C. (BMC (part of Springer Nature), 2018-10-16)
    It is a well-known fact that DHEA declines on ageing and that it is linked to ageing-related neurodegeneration, which is characterised by gradual cognitive decline. Although DHEA is also associated with inflammation in ...
  • The impact of plasticizer and degree of hydrolysis on free volume of poly(vinyl alcohol) films 

    Fong, Rebecca J.; Robertson, Alexander; Mallon, Peter E.; Thompson, Richard L. (MDPI, 2018-05)
    ENGLISH ABSTRACT: The effect of plasticizer species and the degree of hydrolysis (DH) on the free volume properties of poly(vinyl alcohol) (PVA) were studied using positron annihilation lifetime spectroscopy. Both glycerol ...
  • Comparative cardio and developmental toxicity induced by the popular medicinal extract of Sutherlandia frutescens (L.) R.Br. detected using a zebrafish Tuebingen embryo model 

    Chen, Longsheng; Xu, Minjie; Gong, Zhunan; Zonyane, Samkele; Xu, Shuwen; Makunga, Nokwanda P. (BMC (part of Springer Nature), 2018-10-05)
    Background: Sutherlandia frutescens is one of the most promising commercialized, indigenous and medicinal plants of South Africa that is used as an immune-booster, and a traditional treatment for cancer. However, few studies ...
  • A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats 

    Ephraim, Mabhida Sihle; Rabia, Johnson; Musawenkosi, Ndlovu; Felicia, Sangweni Nonhlakanipho; Johan, Louw; Andrew, Opoku; Anthony, Mosa Rebamang (BMC (part of Springer Nature), 2018-10-01)
    Background: A substantial literature supports antidiabetic properties of the lanosteryl triterpene (methyl-3β- hydroxylanosta-9,24-dien-21-oate, RA-3) isolated from Protorhus longifolia stem bark. However, the ...
  • A review : the fate of bacteriocins in the human gastro-intestinal tract : do they cross the gut–blood barrier? 

    Dicks, Leon M. T.; Dreyer, Leane; Smith, Carine; Van Staden, Anton D. (Frontiers Media, 2018)
    The intestinal barrier, consisting of the vascular endothelium, epithelial cell lining, and mucus layer, covers a surface of about 400 m2. The integrity of the gut wall is sustained by transcellular proteins forming tight ...
  • Using rodent models to simulate stress of physiologically relevant severity : when, why and how 

    Smith, Carine (InTech, Rijeka, Croatia, 2012)
    Given the demands of modern life, it is no wonder that the concept of stress has become a household topic for discussion. Also in the academic realm the phenomenon which is stress, is topping the charts in terms of ...
  • Chemoprevention of LA7-induced mammary tumor growth by SM6Met, a well-characterized cyclopia extract 

    Oyenihi, Omolola R.; Krygsman, Annadie; Verhoog, Nicolette; De Beer, Dalene; Saayman, Michael J.; Mouton, Thys M.; Louw, Ann (Frontiers, 2018)
    Breast cancer (BC) is the leading cause of cancer-related deaths in women. Chemoprevention of BC by using plant extracts is gaining attention. SM6Met, a wellcharacterized extract of Cyclopia subternata with reported ...
  • Novel role for receptor dimerization in post-translational processing and turnover of the GRα 

    Louw, Ann; Wilkinson, Legh; Verhoog, Nicolette (Nature, 2018)
    Glucocorticoids (GCs), acting via the glucocorticoid receptor (GRα), remain the mainstay therapeutic choice for the treatment of inflammation. However, chronic GC use, aside from generating undesirable side-effects, ...
  • The role of bile acids in nutritional support 

    Van Niekerk, Gustav; Davis, Tanja; De Villiers, Willem; Engelbrecht, Anna-Mart (BioMed Central, 2018-09-30)
    Abstract: Nutritional support continues to receive much attention as a possible intervention to prevent loss of lean tissue mass, promote recovery and re-establish proper immune function in critical care patients. Yet there ...

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