Browsing Nuclear Medicine by Title
Now showing items 18-36 of 36
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Metastatiese verkalkinge soos aangetoon met tegnesium-99m-pirofosfaatbeenflikkergrafie : gevalbesprekinge
(Health & Medical Publishing Group, 1982)Two cases of chronic renal failure showing very interesting technetium-99m-pyrophosphate bone scans are presented. In both cases striking uptake of activity was shown in the left ventricle of the heart, the mucosa of the ... -
Methamphetamine dependence with and without psychotic symptoms : a multi-modal brain imaging study
(Elsevier, 2018)Objective: Methamphetamine dependence can lead to psychotic symptoms which may be mediated by frontal, striatal, limbic, and thalamic regions. There are few neuroimaging data that allow comparison of individuals with ... -
Monitoring various eluate characteristics of the iThemba LABS SnO2-based 68Ge/68Ga generator over time and validation of quality control methods for the radiochemical purity assessment of 68Ga-labelled DOTA peptide formulations
(Stellenbosch : Stellenbosch University, 2017-03)ENGLISH SUMMARY : PET imaging with gallium-68 (68Ga) has become widely used due to the availability of 68Ge/68Ga generators and DOTA-derivatised peptide ligands for radiolabelling. The purpose of this study was to monitor ... -
Nuclear medicine in South Africa
(HMPG, 2003-08)ENGLISH ABSTRACT: Why should an issue of CME, a publication primarily directed at generalists, be devoted to nuclear medicine? I am reminded from time to time of how unfamiliar many of my colleagues are with this ... -
Optimal utilization of gamma camera time in Tc-99m MDP bone scintigraphy
(Stellenbosch : University of Stellenbosch, 2007-03)Introduction: Whole body bone scintigraphy with Tc-99m MDP is able to provide a survey of the entire skeleton. The question arises if it is mandatory to perform a whole body bone scan in all patients, irrespective of the ... -
Pulmonary embolism diagnosis : a clinical comparison between conventional planar and SPECT V/Q imaging using Krypton 81m – with CTPA as the gold standard
(Stellenbosch : University of Stellenbosch, 2010-03)ENGLISH ABSTRACT: Single photon emission computed tomography (SPECT) with a superior contrast resolution has been shown to be more sensitive and specific with a lower nondiagnostic rate than planar imaging in many nuclear ... -
Quantifying the risks of radiation exposure
(Health & Medical Publishing Group, 1986-09)The considerations leading to the recommendation of dose-equivalent limits by the International Commision for Radiological Protection are outlined. The dose-equivalent limits are based on radiation risk factors estimated ... -
Radiosensitisation of low HER-2 expressing human breast cancer cell lines
(Stellenbosch : Stellenbosch University, 2015-04)ENGLISH ABSTRACT: Breast Cancer remains one of the world’s leading causes of cancer related deaths amongst women. Its treatment has evolved from invasive, highly toxic therapies to treatments that possess a higher ... -
Response to radioiodine in male hyperthyroid patients at Tygerberg Hospital
(Stellenbosch : University of Stellenbosch, 2009-03)ENGLISH ABSTRACT: Radioiodine therapy is reputed to yield poorer results in male patients than in females. We retrospectively reviewed the records of 308 patients treated with radioiodine-131 (RAI) for Graves’ disease ... -
Social anxiety disorder : Functional neuroimaging and social cognitive features
(Stellenbosch : Stellenbosch University, 2018-03)ENGLISH SUMMARY : Neuroimaging has enabled important progress in understanding the neurobiology of social anxiety disorder (SAD). Functional neuroimaging experiments in SAD have mostly focused on regional neural activity ... -
Targeting the EBFR and PI3K pathways as a therapeutic strategy for prostate cancer
(Stellenbosch : Stellenbosch University, 2015-04)ENGLISH ABSTRACT: Targeted therapy for prostate cancer may offer potential improvement over current conventional therapies because of its specificity. Although conventional treatments are effective, they are not curative ... -
Two simple inexpensive photographic methods for viewing ECG-gated radionuclide blood pool images
(HMPG, 1979-04)Although the ECG-gated radionuclide blood pool scan (GBPS) has become an established method for studying regional myocardial wall motion, it is usually performed with the aid of an expensive computer system. A simple, ... -
An update on the management of breast cancer in Africa
(BioMed Central, 2017-02-14)ENGLISH SUMMARY : Background: There is limited information about the challenges of cancer management and attempts at improving outcomes in Africa. Even though South and North Africa are better resourceds to tackle the ... -
Validation of a cost-effective alternative for a radiochromatography method to be used in a developing country
(SpringerOpen (part of Springer Nature), 2020-04-10)Introduction: The radiochemical purity (RCP) of technetium-99m labelled radiopharmaceuticals (RP) is important to ensure optimal scintigraphic image quality. In low-income settings, it may not be possible to use compendial ... -
Validation of equations to estimate glomerular filtration rate in South Africans of mixed ancestry
(Health & Medical Publishing Group, 2020-02-26)Background. The Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations are two commonly used formulae to estimate glomerular filtration rate (GFR) in adults. ... -
Validation of radiochemical purity analysis methods used in two tertiary public hospitals in South Africa
(Stellenbosch : Stellenbosch University, 2016-03)ENGLISH SUMMARY : Radiopharmaceutical kits are supplied by manufacturers with package inserts containing information about the kit including validated methods of preparation and radiochemical purity (RCP) analysis. Validated ... -
Ventilasiestudies van die long met kripton-81m
(HMPG, 1981-08)During a 2-year study period it was found that krypton-81m was useful in routine clinical practice. During this period 1563 technetium-99m perfusion studies and 807 krypton-81m ventilation studies were performed. A distinct ... -
Die waarde van speldgatkollimator-opnames in die flikkergrafiese diagnose van werwelpatologie
(Health & Medical Publishing Group, 1989)Recent findings suggested a possible role for pinhole collimator scintigraphy to differentiate between metastases, infection and fractures of the vertebrae. The aim of this study was to verify these findings and to ascertain ... -
Working towards the implementaion of an international accreditation programme in a Nuclear Medicine Department of a South African teaching hospital
(Stellenbosch : Stellenbosch University, 2005-04)ENGLISH ABSTRACT: Introduction: Quality assurance in Nuclear Medicine is of utmost importance in order to ensure optimal scintigraphic results and correct patient management. A customised Quality Management System (QMS) ...