Browsing Nuclear Medicine by Title
Now showing items 12-31 of 36
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First-pass determination of the right ventricular ejection fraction using two regions of interest and the right anterior oblique view
(HMPG, 1984)The right ventricular ejection fraction (RVEF) was determined on the right anterior oblique view in 9 patients during the first pass of a bolus of technetium-99m employing a gamma camera with high count-rate capability. ... -
Glomerular filtration rate measurement and estimation : improvement and validation of existing methods
(Stellenbosch : Stellenbosch University, 2019-12)ENGLISH SUMMARY : Glomerular filtration rate (GFR) is regarded as the best measure of kidney function. It can either be measured or estimated. This dissertation aims to provide a better understanding of GFR measurement in ... -
Hybrid imaging using low-dose, localizing computed tomography enhances lesion localization in renal hyperparathyroidism
(Lippincott, Williams & Wilkins, 2014-03)Background Preoperative localization of parathyroid lesions is potentially beneficial in renal patients with hyperparathyroidism. The aim of this study was to determine the localizing value of hybrid single-photon emission ... -
Imaging of renal hyperparathyroidism using SPECT/CT with low-dose localizing CT
(Stellenbosch : Stellenbosch University, 2013-12)ENGLISH ABSTRACT: Background: Hybrid imaging using single photon emission computed tomography/low dose (x-ray) computed tomography (SPECT/LDCT) is of benefit in preoperative scintigraphy of primary hyperparathyroidism. The ... -
Investigation into various aspects of radiolabelling somatostatin peptide derivatives with 68Ga eluted from a SnO2-based 68Ge/68Ga generator
(Stellenbosch : Stellenbosch University, 2018-03)ENGLISH SUMMARY : 68Ge/68Ga generators ensure the supply of 68Ga for positron emission tomography (PET), for instance for somatostatin receptor imaging with 68Ga-DOTA-labelled somatostatin analogues. There are various ... -
An investigation of the contribution of Single Photon Emission Computed Tomography to the diagnosis of skeletal metastases using bone scan in the African context
(Stellenbosch : Stellenbosch University, 2003-12)ENGLISH ABSTRACT: Planar bone scintigraphy is highly sensitive but it may not be sensitive enough to detect subtle lesions in complex bony structures such as the spine. The accurate anatomic localisation of lesions in ... -
Metastatiese verkalkinge soos aangetoon met tegnesium-99m-pirofosfaatbeenflikkergrafie : gevalbesprekinge
(Health & Medical Publishing Group, 1982)Two cases of chronic renal failure showing very interesting technetium-99m-pyrophosphate bone scans are presented. In both cases striking uptake of activity was shown in the left ventricle of the heart, the mucosa of the ... -
Methamphetamine dependence with and without psychotic symptoms : a multi-modal brain imaging study
(Elsevier, 2018)Objective: Methamphetamine dependence can lead to psychotic symptoms which may be mediated by frontal, striatal, limbic, and thalamic regions. There are few neuroimaging data that allow comparison of individuals with ... -
Monitoring various eluate characteristics of the iThemba LABS SnO2-based 68Ge/68Ga generator over time and validation of quality control methods for the radiochemical purity assessment of 68Ga-labelled DOTA peptide formulations
(Stellenbosch : Stellenbosch University, 2017-03)ENGLISH SUMMARY : PET imaging with gallium-68 (68Ga) has become widely used due to the availability of 68Ge/68Ga generators and DOTA-derivatised peptide ligands for radiolabelling. The purpose of this study was to monitor ... -
Nuclear medicine in South Africa
(HMPG, 2003-08)ENGLISH ABSTRACT: Why should an issue of CME, a publication primarily directed at generalists, be devoted to nuclear medicine? I am reminded from time to time of how unfamiliar many of my colleagues are with this ... -
Optimal utilization of gamma camera time in Tc-99m MDP bone scintigraphy
(Stellenbosch : University of Stellenbosch, 2007-03)Introduction: Whole body bone scintigraphy with Tc-99m MDP is able to provide a survey of the entire skeleton. The question arises if it is mandatory to perform a whole body bone scan in all patients, irrespective of the ... -
Pulmonary embolism diagnosis : a clinical comparison between conventional planar and SPECT V/Q imaging using Krypton 81m – with CTPA as the gold standard
(Stellenbosch : University of Stellenbosch, 2010-03)ENGLISH ABSTRACT: Single photon emission computed tomography (SPECT) with a superior contrast resolution has been shown to be more sensitive and specific with a lower nondiagnostic rate than planar imaging in many nuclear ... -
Quantifying the risks of radiation exposure
(Health & Medical Publishing Group, 1986-09)The considerations leading to the recommendation of dose-equivalent limits by the International Commision for Radiological Protection are outlined. The dose-equivalent limits are based on radiation risk factors estimated ... -
Radiosensitisation of low HER-2 expressing human breast cancer cell lines
(Stellenbosch : Stellenbosch University, 2015-04)ENGLISH ABSTRACT: Breast Cancer remains one of the world’s leading causes of cancer related deaths amongst women. Its treatment has evolved from invasive, highly toxic therapies to treatments that possess a higher ... -
Response to radioiodine in male hyperthyroid patients at Tygerberg Hospital
(Stellenbosch : University of Stellenbosch, 2009-03)ENGLISH ABSTRACT: Radioiodine therapy is reputed to yield poorer results in male patients than in females. We retrospectively reviewed the records of 308 patients treated with radioiodine-131 (RAI) for Graves’ disease ... -
Social anxiety disorder : Functional neuroimaging and social cognitive features
(Stellenbosch : Stellenbosch University, 2018-03)ENGLISH SUMMARY : Neuroimaging has enabled important progress in understanding the neurobiology of social anxiety disorder (SAD). Functional neuroimaging experiments in SAD have mostly focused on regional neural activity ... -
Targeting the EBFR and PI3K pathways as a therapeutic strategy for prostate cancer
(Stellenbosch : Stellenbosch University, 2015-04)ENGLISH ABSTRACT: Targeted therapy for prostate cancer may offer potential improvement over current conventional therapies because of its specificity. Although conventional treatments are effective, they are not curative ... -
Two simple inexpensive photographic methods for viewing ECG-gated radionuclide blood pool images
(HMPG, 1979-04)Although the ECG-gated radionuclide blood pool scan (GBPS) has become an established method for studying regional myocardial wall motion, it is usually performed with the aid of an expensive computer system. A simple, ... -
An update on the management of breast cancer in Africa
(BioMed Central, 2017-02-14)ENGLISH SUMMARY : Background: There is limited information about the challenges of cancer management and attempts at improving outcomes in Africa. Even though South and North Africa are better resourceds to tackle the ... -
Validation of a cost-effective alternative for a radiochromatography method to be used in a developing country
(SpringerOpen (part of Springer Nature), 2020-04-10)Introduction: The radiochemical purity (RCP) of technetium-99m labelled radiopharmaceuticals (RP) is important to ensure optimal scintigraphic image quality. In low-income settings, it may not be possible to use compendial ...
