Now showing items 1-2 of 2
Anti-inflammatory effects of reactive oxygen species : a multi-valued logical model validated by formal concept analysis
(BioMed Central, 2014-09)
Background: Recent findings suggest that in pancreatic acinar cells stimulated with bile acid, a pro-apoptotic effect of reactive oxygen species (ROS) dominates their effect on necrosis and spreading of inflammation. The ...
Death domain signaling by disulfide-linked dimers of the p75 neurotrophin receptor mediates neuronal death in the CNS
(Society for Neuroscience, 2016-05-18)
The p75 neurotrophin receptor (p75NTR) mediates neuronal death in response to neural insults by activating a caspase apoptotic pathway. The oligomeric state and activation mechanism that enable p75NTR to mediate these ...