Browsing Research Articles (Stellenbosch Institute for Advanced Studies) by Title
Now showing items 31-50 of 67
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Image-based mHealth for remote diagnostic assistance a means to promote equity in quality care
(Taylor & Francis Open, 2017)No abstract -
An integrated approach to processing WHO-2016 verbal autopsy data : the InterVA-5 model
(BMC (part of Springer Nature), 2019-05-30)Background: Verbal autopsy is an increasingly important methodology for assigning causes to otherwise uncertified deaths, which amount to around 50% of global mortality and cause much uncertainty for health planning. The ... -
An integrative network-driven pipeline for systematic identification of lncRNA-associated regulatory network motifs in metastatic melanoma
(BMC (part of Springer Nature), 2020-07-23)Background: Melanoma phenotype and the dynamics underlying its progression are determined by a complex interplay between different types of regulatory molecules. In particular, transcription factors (TFs), microRNAs ... -
Lateralization of the avian magnetic compass : analysis of its early plasticity
(MDPI, 2017)In European Robins, Erithacus rubecula, the magnetic compass is lateralized in favor of the right eye/left hemisphere of the brain. This lateralization develops during the first winter and initially shows a great plasticity. ... -
Mathematical models and the fight against diseases in Africa
(Academy of Science for South Africa, 2003)A new initiative proposes to build capacity across Africa to collect data and conduct quantitative analyses necessary to understand the dynamics of major diseases afflicting the continent, with an initial emphasis on HIV/AIDS. -
Mce3R stress-resistance pathway is vulnerable to small-molecule targeting that improves tuberculosis drug activities
(American Chemical Society, 2019)One-third of the world’s population carries Mycobacterium tuberculosis (Mtb), the infectious agent that causes tuberculosis (TB), and every 17 s someone dies of TB. After infection, Mtb can live dormant for decades in ... -
Medical mobile technologies – what is needed for a sustainable and scalable implementation on a global scale?
(Taylor & Francis Open, 2017)Current advances within medical technology show great potential from a global health perspective. Inexpensive, effective solutions to common problems within diagnostics, medical procedures and access to medical information ... -
Observed full blood count and lymphocyte subset values in a cohort of clinically healthy South African children from a semi-informal settlement in Cape Town
(Health & Medical Publishing Group, 2015-09)Background. The paediatric full blood count and lymphocyte subset reference intervals used by the National Health Laboratory Service (NHLS), South Africa (SA), are taken from two international reference interval publications. ... -
On the modularity of the intrinsic flexibility of the µ opioid receptor : a computational study
(Public Library of Science, 2015)The µ opioid receptor (µOR), the principal target to control pain, belongs to the G protein-coupled receptors (GPCRs) family, one of the most highlighted protein families due to their importance as therapeutic targets. The ... -
On the physiology of jouissance : interpreting the mesolimbic dopaminergic reward functions from a psychoanalytic perspective
(Frontiers, 2013-11-06)Jouissance is a Lacanian concept, infamous for being impervious to understanding and which expresses the paradoxical satisfaction that a subject may derive from his symptom. On the basis of Freud’s “experience of satisfaction” ... -
Overcoming violence - a basic task of Christian churches
(AOSIS Publishing, 2011-12-12)In this article – based on the second of two keynote lectures at a conference on violence – the view is developed that the task of the church with respect to violence consists mainly in overcoming violence. In the first ... -
Parameter identifiability and sensitivity analysis predict targets for enhancement of STAT1 activity in pancreatic cancer and stellate cells
(Public Library of Science, 2012-12)The present work exemplifies how parameter identifiability analysis can be used to gain insights into differences in experimental systems and how uncertainty in parameter estimates can be handled. The case study, presented ... -
Primary processing neuropils associated with the malleoli of camel spiders (Arachnida, Solifugae) : a re-evaluation of axonal pathways
(BMC (part of Springer Nature), 2019-08-02)Background - Arachnids possess highly specialized and unorthodox sense organs, such as the unique pectines of Scorpiones and the malleoli of Solifugae. While the external morphology, numbers, and shapes of sensory organs ... -
Progress in human embryonic stem cell research in the United States between 2001 and 2010
(Public Library of Science, 2015)On August 9th, 2001, the federal government of the United States announced a policy restricting federal funds available for research on human embryonic stem cell (hESCs) out of concern for the “vast ethical mine fields” ... -
Projected climatic and hydrologic changes to lake Victoria Basin Rivers under three RCP emission scenarios for 2015–2100 and impacts on the water sector
(MDPI, 2019)Rivers in the Lake Victoria Basin support a multitude of ecosystem services, and the economies of the riparian countries (Kenya, Tanzania, Uganda, Rwanda, and Burundi) rely on their discharge, but projections of their ... -
Religion and violence in a globalised world
(AOSIS Publishing, 2011-11-18)Violent religious extremism is seen as one of the mega-problems of the 21st century. This article – based on a key lecture at the conference on ‘Violence in a democratic South Africa’ at the University of Pretoria and ... -
Review and recommendations on management of adult female thalassemia patients with hypogonadism based on literature review and experience of ICET-A network specialists
(PAGEpress, 2017)Background: Multi-transfused thalassemia major (TM) patients frequently develop severe endocrine complications, mainly due to iron overload, anemia and chronic liver disease, which require prompt diagnosis, treatment and ... -
Risky sexual behaviour and contraceptive use in contexts of displacement : insights from a cross-sectional survey of female adolescent refugees in Ghana
(BMC (part of Springer Nature), 2019-08-16)Background: Difficulty in accessing sexual and reproductive healthcare is one of the challenges young refugee women face worldwide, in addition to sexual exploitation, violence and abuse. Although Ghana hosts several ... -
The role of theory and modeling in medical research
(Frontiers Media, 2013-12-19)No abstract available. -
Romans 13: 1-7 : a review of post-1989 readings
(Stellenbosch University' Faculty of Theology, 2012)Romans 13:1-7 has remained a challenge for interpreters throughout the history of the New Testament. A previous study investigated the actual readings of the passage during the political transition in South Africa. The ...
