Browsing Research Articles (Stellenbosch Institute for Advanced Studies) by Title
Now showing items 23-42 of 67
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Effectiveness of home-based nutritional counselling and support on exclusive breastfeeding in urban poor settings in Nairobi : a cluster randomized controlled trial
(BMC (part of Springer Nature), 2017)Background: Exclusive breastfeeding (EBF) improves infant health and survival. We tested the effectiveness of a homebased intervention using Community Health Workers (CHWs) on EBF for six months in urban poor settings in ... -
Effectiveness of the baby-friendly community initiative in promoting exclusive breastfeeding among HIV negative and positive mothers : a randomized controlled trial in Koibatek Sub-County, Baringo, Kenya
(BMC (part of Springer Nature), 2020-07-14)Background: Although the baby-friendly community initiative (BFCI) has been proposed as a community-level approach to improve infant feeding practices, there is little data on its variation in effectiveness by HIV status. ... -
Enabling multiscale modeling in systems medicine
(BioMed Central, 2014-03)[See article for abstract]. -
Epigenetic regulation of lateralized fetal spinal gene expression underlies hemispheric asymmetries
(eLife Sciences Publications, 2017)Lateralization is a fundamental principle of nervous system organization but its molecular determinants are mostly unknown. In humans, asymmetric gene expression in the fetal cortex has been suggested as the molecular basis ... -
Evolution of computational models in BioModels Database and the Physiome Model Repository
(BioMed Central, 2018-04-12)ENGLISH SUMMARY : Background: A useful model is one that is being (re)used. The development of a successful model does not finish with its publication. During reuse, models are being modified, i.e. expanded, corrected, and ... -
Factors influencing the use of supervised delivery services in Garu-Tempane District, Ghana
(BMC (part of Springer Nature), 2019-04-27)Background: There is evidence that supervised delivery has the potential to improve birth outcomes for both women and newborns. However, not all women especially in low-income settings like Ghana use supervised delivery ... -
General criterion for harmonicity
(American Physical Society, 2017)Inspired by Kubo-Anderson Markov processes, we introduce a new class of transfer matrices whose largest eigenvalue is determined by a simple explicit algebraic equation. Applications include the free energy calculation for ... -
How spatial scale shapes the generation and management of multiple ecosystem services
(Ecological Society of America, 2017)The spatial extent of ecological processes has consequences for the generation of ecosystem services related to them. However, management often fails to consider issues of scale when targeting ecological processes underpinning ... -
Image-based mHealth for remote diagnostic assistance a means to promote equity in quality care
(Taylor & Francis Open, 2017)No abstract -
An integrated approach to processing WHO-2016 verbal autopsy data : the InterVA-5 model
(BMC (part of Springer Nature), 2019-05-30)Background: Verbal autopsy is an increasingly important methodology for assigning causes to otherwise uncertified deaths, which amount to around 50% of global mortality and cause much uncertainty for health planning. The ... -
An integrative network-driven pipeline for systematic identification of lncRNA-associated regulatory network motifs in metastatic melanoma
(BMC (part of Springer Nature), 2020-07-23)Background: Melanoma phenotype and the dynamics underlying its progression are determined by a complex interplay between different types of regulatory molecules. In particular, transcription factors (TFs), microRNAs ... -
Lateralization of the avian magnetic compass : analysis of its early plasticity
(MDPI, 2017)In European Robins, Erithacus rubecula, the magnetic compass is lateralized in favor of the right eye/left hemisphere of the brain. This lateralization develops during the first winter and initially shows a great plasticity. ... -
Mathematical models and the fight against diseases in Africa
(Academy of Science for South Africa, 2003)A new initiative proposes to build capacity across Africa to collect data and conduct quantitative analyses necessary to understand the dynamics of major diseases afflicting the continent, with an initial emphasis on HIV/AIDS. -
Mce3R stress-resistance pathway is vulnerable to small-molecule targeting that improves tuberculosis drug activities
(American Chemical Society, 2019)One-third of the world’s population carries Mycobacterium tuberculosis (Mtb), the infectious agent that causes tuberculosis (TB), and every 17 s someone dies of TB. After infection, Mtb can live dormant for decades in ... -
Medical mobile technologies – what is needed for a sustainable and scalable implementation on a global scale?
(Taylor & Francis Open, 2017)Current advances within medical technology show great potential from a global health perspective. Inexpensive, effective solutions to common problems within diagnostics, medical procedures and access to medical information ... -
Observed full blood count and lymphocyte subset values in a cohort of clinically healthy South African children from a semi-informal settlement in Cape Town
(Health & Medical Publishing Group, 2015-09)Background. The paediatric full blood count and lymphocyte subset reference intervals used by the National Health Laboratory Service (NHLS), South Africa (SA), are taken from two international reference interval publications. ... -
On the modularity of the intrinsic flexibility of the µ opioid receptor : a computational study
(Public Library of Science, 2015)The µ opioid receptor (µOR), the principal target to control pain, belongs to the G protein-coupled receptors (GPCRs) family, one of the most highlighted protein families due to their importance as therapeutic targets. The ... -
On the physiology of jouissance : interpreting the mesolimbic dopaminergic reward functions from a psychoanalytic perspective
(Frontiers, 2013-11-06)Jouissance is a Lacanian concept, infamous for being impervious to understanding and which expresses the paradoxical satisfaction that a subject may derive from his symptom. On the basis of Freud’s “experience of satisfaction” ... -
Overcoming violence - a basic task of Christian churches
(AOSIS Publishing, 2011-12-12)In this article – based on the second of two keynote lectures at a conference on violence – the view is developed that the task of the church with respect to violence consists mainly in overcoming violence. In the first ... -
Parameter identifiability and sensitivity analysis predict targets for enhancement of STAT1 activity in pancreatic cancer and stellate cells
(Public Library of Science, 2012-12)The present work exemplifies how parameter identifiability analysis can be used to gain insights into differences in experimental systems and how uncertainty in parameter estimates can be handled. The case study, presented ...
