Browsing Stellenbosch Institute for Advanced Studies (STIAS) by Title

Now showing items 1-7 of 7

    • Age-dependent effects of UCP2 deficiency on experimental acute pancreatitis in mice 

      Muller, Sarah; Kaiser, Hannah; Kruger, Burkhard; Fitzner, Brit; Lange, Falko; Bock, Cristin N.; Nizze, Horst; Ibrahim, Saleh M.; Fuellen, Georg; Wolkenhauer, Olaf; Jaster, Robert (PLoS, 2014-04-10)
      Reactive oxygen species (ROS) have been implicated in the pathogenesis of acute pancreatitis (AP) for many years but experimental evidence is still limited. Uncoupling protein 2 (UCP2)-deficient mice are an accepted model ...

    • “Deeper into a hole?” : borrowing and lending in South Africa 

      James, Deborah (University of Chicago Press Journals, 2014-08)
      In South Africa, with upward mobility much aspired to but seldom attained, householders must spend money they have not yet earned. Borrowing both from formal institutions and smaller moneylenders (legal and illegal) positions ...

    • Enabling multiscale modeling in systems medicine 

      Wolkenhauer, Olaf; Auffray, Charles; Brass, Olivier; Clairambault, Jean; Deutsch, Andreas; Drasdo, Dirk; Gervasio, Francesco; Preziosi, Luigi; Maini, Philip; Marciniak-Czochra, Anna; Kossow, Christina; Kuepfer, Lars; Rateitschak, Katja; Ramis-Conde, Ignacio; Ribba, Benjamin; Schuppert, Andreas; Smallwood, Rod; Stamatakos, Georgios; Winter, Felix; Byrne, Helen (BioMed Central, 2014-03)
      [See article for abstract].

    • Observed full blood count and lymphocyte subset values in a cohort of clinically healthy South African children from a semi-informal settlement in Cape Town 

      Lawrie, Denise; Payne, Helen; Nieuwoudt, Martin; Glencross, Deborah Kim (Health & Medical Publishing Group, 2015-09)
      Background. The paediatric full blood count and lymphocyte subset reference intervals used by the National Health Laboratory Service (NHLS), South Africa (SA), are taken from two international reference interval publications. ...

    • Parameter identifiability and sensitivity analysis predict targets for enhancement of STAT1 activity in pancreatic cancer and stellate cells 

      Rateitschak, Katja; Winter, Felix; Lange, Falko; Jaster, Robert; Wolkenhauer, Olaf (Public Library of Science, 2012-12)
      The present work exemplifies how parameter identifiability analysis can be used to gain insights into differences in experimental systems and how uncertainty in parameter estimates can be handled. The case study, presented ...

    • Progress in human embryonic stem cell research in the United States between 2001 and 2010 

      Vakili, Keyvan; McGahan, Anita M.; Rezaie, Rahim; Mitchell, Will; Daar, Abdallah S. (Public Library of Science, 2015)
      On August 9th, 2001, the federal government of the United States announced a policy restricting federal funds available for research on human embryonic stem cell (hESCs) out of concern for the “vast ethical mine fields” ...

    • A view from Silicon Valley 

      Botha, Roelof (Stellenbosch : Stellenbosch University, 2012-04-10)
      As per: http://blogs.sun.ac.za/news/2012/03/26/internet-entrepreneur-roelof-botha-at-su-on-april-10. "Internet entrepreneur and venture capital specialist, Roelof Botha, will visit Stellenbosch University (SU) on 10 April ...