Carcinoma of the gallbladder - a possible regional predisposition in the Western Cape and the Northern Cape
Date
1995
Authors
Warren B.L.
Marais A.W.
Journal Title
Journal ISSN
Volume Title
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Abstract
An analysis of 19 patients with confirmed carcinoma of the gallbladder who were treated over a period of 68 months emphasised known clinical features of the disease, i.e. nonspecific symptomatology, late presentation and poor prognosis. Comparison with 883 patients undergoing surgery for benign calculous biliary tract disease during the same period identified a more advanced mean age (67,0 v. 55,3 years), larger mean maximum stone diameter (20,3 v. 11,9 mm) and a higher proportion of patients resident in the Cape interior and west coast region (57,8% v. 11,8%) as features associated with carcinoma of the gallbladder. Further investigation of the regional predisposition suggested by this study may identify new factors linked to the development of gallbladder cancer.
Description
Keywords
adenocarcinoma, adult, age, aged, article, cancer staging, cancer susceptibility, cholecystectomy, clinical article, comparative study, controlled study, female, gallbladder carcinoma, gallstone, geographic distribution, human, male, prognosis, symptomatology, Adenocarcinoma, Adolescent, Adult, Aged, Aged, 80 and over, Carcinoma, Squamous Cell, Child, Cholangiography, Cholelithiasis, Female, Gallbladder Neoplasms, Hepatic Duct, Common, Humans, Male, Middle Aged, Risk Factors, South Africa
Citation
South African Journal of Surgery
33
4
33
4