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Directly interrogating single quantum dot labelled UvrA2 molecules on DNA tightropes using an optically trapped nanoprobe

Simons, Michelle; Pollard, Mark R.; Hughes, Craig D.; Ward, Andrew D.; Van Houten, Bennett; Towrie, Mike; Botchway, Stan W.; Parker, Anthony W.; Kad, Neil M. (Springer Nature, 2016)

In this study we describe a new methodology to physically probe individual complexes formed between proteins and DNA. By combining nanoscale, high speed physical force measurement with sensitive fluorescence imaging we ...