Endopap®- versus Pipelle®-sampling in the diagnosis of postmenopausal endometrial disease

Date
1996
Authors
Van Den Bosch T.
Vandendael A.
Wranz P.A.B.
Lombard C.J.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Objective: To evaluate the accuracy of Endopap®- and Pipelle®-sampling in the diagnosis of postmenopausal disease. Study Design: Observational study in the setting of a University Hospital. One hundred and six consecutive postmenopausal women presenting with uterine bleeding or endometrial cells on cervical cytology underwent an Endopap® sampling as well as a Pipelle® biopsy. Thereafter, 89 of those women underwent a hysteroscopy and curettage (n = 71) or a hysterectomy (n = 18). The diagnostic accuracy of Pipelle® and Endopap® was assessed against the final diagnosis. Results: Endometrial carcinoma was found in five cases (6%), benign disease in 34 (38%). The sensitivity of Endopap® and Pipelle® for the detection of endometrial disease was 56 and 51%, respectively, with a specificity of 94 and 100%, respectively. The sensitivity for endometrial carcinoma was 80% for Endopap® and 100% for Pipelle®. Conclusion: Our data tend to favor Pipelle® against Endopap® as diagnostic tool in endometrial disease in symptomatic postmenopausal women.
Description
Keywords
adult, article, cancer diagnosis, clinical trial, controlled clinical trial, controlled study, diagnostic accuracy, endometriosis, endometrium carcinoma, female, human, human tissue, major clinical study, postmenopause, priority journal, sampling, biopsy, comparative study, differential diagnosis, endometrium, endometrium tumor, instrumentation, pathology, sensitivity and specificity, uterus bleeding, uterus disease, Biopsy, Diagnosis, Differential, Endometrial Neoplasms, Endometrium, Female, Humans, Postmenopause, Sensitivity and Specificity, Uterine Diseases, Uterine Hemorrhage
Citation
European Journal of Obstetrics Gynecology and Reproductive Biology
64
1