• Epigenetics and proteomics join transcriptomics in the quest for tuberculosis biomarkers 

      Esterhuyse, Maria M.; Weiner, January; Caron, Etienne; Loxton, Andre G.; Iannaccone, Marco; Wagman, Chandre; Saikali, Philippe; Stanley, Kim; Wolski, Witold E.; Mollenkopf, Hans-Joachim; Schick, Matthias; Aebersold, Ruedi; Linhart, Heinz; Walzl, Gerhard; Kaufmann, Stefan H. E. (American Society for Microbiology, 2015-09-15)
      An estimated one-third of the world’s population is currently latently infected with Mycobacterium tuberculosis. Latent M. tuberculosis infection (LTBI) progresses into active tuberculosis (TB) disease in ~5 to 10% of ...
    • Successful TB treatment induces B-cells expressing FASL and IL5RA mRNA 

      Van Rensburg, Ilana C.; Wagman, Chandre; Stanley, Kim; Beltran, Caroline; Ronacher, Katharina; Walzl, Gerhard; Loxton, Andre G. (Impact Journals, 2016-09)
      ENGLISH ABSTRACT: Activated B-cells increase T-cell behaviour during autoimmune disease and other infections by means of cytokine production and antigen-presentation. Functional studies in experimental autoimmune ...