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Now showing items 1-3 of 3
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Diagnostic potential of novel salivary host biomarkers as candidates for the immunological diagnosis of tuberculosis disease and monitoring of tuberculosis treatment response
Jacobs, Ruschca; Maasdorp, Elizna; Malherbe, Stephanus; Loxton, Andre G.; Stanley, Kim; Van Der Spuy, Gian; Walzl, Gerhard; Chegou, Novel N. (Public Library of Science, 2016-08-03)Background: There is an urgent need for new tools for the early diagnosis of TB disease and monitoring of the response to treatment, especially in resource-constrained settings. We investigated the usefulness of host ... -
Identification of novel host biomarkers in plasma as candidates for the immunodiagnosis of tuberculosis disease and monitoring of tuberculosis treatment response
Jacobs, Ruschca; Malherbe, Stephanus; Loxton, Andre G.; Stanley, Kim; Van Der Spuy, Gian; Walzl, Gerhard; Chegou, Novel N. (Impact Journals, 2016-08-19)ENGLISH ABSTRACT: There is an urgent need for new tools for the rapid diagnosis of tuberculosis disease. We evaluated the potentials of 74 host markers as biomarkers for the immunological diagnosis of tuberculosis and ... -
Towards eliminating bias in cluster analysis of TB genotyped data
Van Schalkwyk, Cari; Cule, Madeleine; Welte, Alex; Van Helden, Paul; Van Der Spuy, Gian; Uys, Pieter (PLOS One, 2012-03)The relative contributions of transmission and reactivation of latent infection to TB cases observed clinically has been reported in many situations, but always with some uncertainty. Genotyped data from TB organisms ...