• Diagnostic potential of novel salivary host biomarkers as candidates for the immunological diagnosis of tuberculosis disease and monitoring of tuberculosis treatment response 

      Jacobs, Ruschca; Maasdorp, Elizna; Malherbe, Stephanus; Loxton, Andre G.; Stanley, Kim; Van Der Spuy, Gian; Walzl, Gerhard; Chegou, Novel N. (Public Library of Science, 2016-08-03)
      Background: There is an urgent need for new tools for the early diagnosis of TB disease and monitoring of the response to treatment, especially in resource-constrained settings. We investigated the usefulness of host ...
    • The functional response of B cells to antigenic stimulation : a preliminary report of latent tuberculosis 

      Du Plessis, Willem J.; Kleynhans, Leanie; Du Plessis, Nelita; Stanley, Kim; Malherbe, Stephanus T.; Maasdorp, Elizna; Ronacher, Katharina; Chegou, Novel N.; Walzl, Gerhard; Loxton, Andre G. (Public Library of Science, 2016-04)
      Mycobacterium tuberculosis (M.tb) remains a successful pathogen, causing tuberculosis disease numbers to constantly increase. Although great progress has been made in delineating the disease, the host-pathogen interaction ...
    • Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment response 

      Malherbe, Stephanus T.; Chen, Ray Y.; Dupont, Patrick; Kant, Ilse; Kriel, Magdalena; Loxton, Andre G.; Smith, Bronwyn; Beltran, Caroline G. G.; Van Zyl, Susan; McAnda, Shirely; Abrahams, Charmaine; Maasdorp, Elizna; Doruyter, Alex; Via, Laura E.; Barry, Clifton E.; Alland, David; Richards, Stephanie G.; Ellman, Annare; Peppard, Thomas; Belisle, John; Tromp, Gerard; Ronacher, Katharina; Warwick, James M.; Winter, Jill; Walzl, Gerhard (SpringerOpen (part of Springer Nature), 2020-02-10)
      Background: There is a growing interest in the use of F-18 FDG PET-CT to monitor tuberculosis (TB) treatment response. Tuberculosis lung lesions are often complex and diffuse, with dynamic changes during treatment ...